Thymonin

Base Information

• Chemical Name: Thymonin
• CAS No.: 76844-67-2
• Molecular Formula: C18H16O8
• Molecular Weight: 360.32
• Hs Code.: 2914509090
• DSSTox Substance ID: DTXSID90331895
• Nikkaji Number: J142.171I
• Wikidata: Q27108437
• Metabolomics Workbench ID: 24557
• ChEMBL ID: CHEMBL478416
• Mol file: 76844-67-2.mol

Synonyms:Thymonin;Mucroflavone B;76844-67-2;Majoranin;5,6,4'-trihydroxy-7,8,3'-trimethoxyflavone;CHEBI:9582;CHEMBL478416;5,6-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-7,8-dimethoxy-4H-1-benzopyran-4-one;SCHEMBL20530430;DTXSID90331895;BDBM50412267;LMPK12111474;5,6-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-7,8-dimethoxychromen-4-one;Q27108437;5,6-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-7,8-dimethoxy-4H-chromen-4-one

Chemical Property of Thymonin

Chemical Property:

• Vapor Pressure: 1.6E-18mmHg at 25°C
• Boiling Point: 669.2°C at 760 mmHg
• Flash Point: 246.5°C
• PSA: 118.59000
• Density: 1.461g/cm³
• LogP: 2.60260
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 4
• Exact Mass: 360.08451746
• Heavy Atom Count: 26
• Complexity: 549

Purity/Quality:

99% ^*data from raw suppliers

Thymonin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=CC(=C1)C2=CC(=O)C3=C(C(=C(C(=C3O2)OC)OC)O)O)O
• Uses: Thymonin is a flavonoid compound with potential antioxidant activity against peroxyl radicals.

Technology Process of Thymonin

There total 1 articles about Thymonin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

8-methoxycirsilineol (16520-78-8) → 5,6,4'-trihydroxy-7,8,3'-trimethoxyflavone (76844-67-2)

Guidance literature:

With hydrogenchloride; In methanol; water; at 100 ℃; for 48h;

DOI:10.1016/S0040-4020(01)91379-1

Reference yield: 10.0%

5,6,4'-trihydroxy-7,8,3'-trimethoxyflavone (76844-67-2) → demethylthymonin (103633-26-7) + 5,8,4'-trihydroxy-6,5,3'-trimethoxyflavone (99615-01-7)

Guidance literature:

With hydrogenchloride; In methanol; water; at 100 ℃; for 4h;

DOI:10.1016/S0040-4020(01)91379-1

Reference yield:

5,6,4'-trihydroxy-7,8,3'-trimethoxyflavone (76844-67-2) → nobiletin (478-01-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 30 percent / 4N HCl / methanol; H₂O / 4 h / 100 °C

With hydrogenchloride; In methanol; water;

DOI:10.1016/S0040-4020(01)91379-1

upstream raw materials:

8-methoxycirsilineol

Downstream raw materials:

demethylthymonin

5,8,4'-trihydroxy-6,5,3'-trimethoxyflavone

nobiletin

Refernces