Ser-gly

Base Information

• Chemical Name: Ser-gly
• CAS No.: 687-63-8
• Molecular Formula: C5H10N2O4
• Molecular Weight: 162.145
• Hs Code.: 2924199090
• DSSTox Substance ID: DTXSID101317330
• Nikkaji Number: J149.642E
• Wikidata: Q27144923
• Metabolomics Workbench ID: 78963
• ChEMBL ID: CHEMBL90610
• Mol file: 687-63-8.mol

Synonyms:H-SER-GLY-OH;ser-gly;687-63-8;L-Serylglycine;Serylglycine;Ser-Gly-OH;CHEMBL90610;CHEBI:74814;NSC 88482;L-seryl-glycine;2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]acetic acid;(S)-2-(2-Amino-3-hydroxyPropanamido)acetic acid;Serinylglycine;Seryl-glycine;Serinyl-Glycine;SG dipeptide;S-G Dipeptide;L-Ser-Gly;L-Serinyl-L-Glycine;Serine Glycine dipeptide;Serine-Glycine dipeptide;SCHEMBL8070171;DTXSID101317330;BDBM50407453;MFCD00037778;AKOS006271475;CS-0367553;2-[(2S)-2-amino-3-hydroxypropanamido]acetic acid;Q27144923

Chemical Property of Ser-gly

Chemical Property:

• Appearance/Colour: White crystalline powder
• Vapor Pressure: 1.03E-15mmHg at 25°C
• Refractive Index: 1.538
• Boiling Point: 577 °C at 760 mmHg
• Flash Point: 302.7 °C
• PSA: 112.65000
• Density: 1.432 g/cm³
• LogP: -1.40200
• Storage Temp.: -15°C
• XLogP3: -4.7
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 162.06405680
• Heavy Atom Count: 11
• Complexity: 159

Purity/Quality:

98%min ^*data from raw suppliers

Ser-Gly-OH,≥97%(HPLC) ≥97%(HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(=O)NCC(=O)O)N)O
• Isomeric SMILES: C([C@@H](C(=O)NCC(=O)O)N)O

Technology Process of Ser-gly

There total 5 articles about Ser-gly which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(Benzyloxycarbonyl)-L-seryl-glycine benzyl ester (2543-27-3) → L-Ser-Gly (687-63-8,113139-74-5)

Guidance literature:

With methanol; palladium; Hydrogenolyse;

Reference yield:

N-(N-benzyloxycarbonyl-L-seryl)-glycine-(4-nitro-benzyl ester) (26054-98-8) → L-Ser-Gly (687-63-8,113139-74-5)

Guidance literature:

With hydrogen; palladium on activated charcoal;

DOI:10.1002/hlca.19620450515

Reference yield:

N-benzyloxycarbonylserylglycine (30735-20-7) → L-Ser-Gly (687-63-8,113139-74-5)

Guidance literature:

With methanol; palladium; Hydrogenolyse;

upstream raw materials:

N-(Benzyloxycarbonyl)-L-seryl-glycine benzyl ester

N-benzyloxycarbonylserylglycine

N-(N-benzyloxycarbonyl-L-seryl)-glycine-(4-nitro-benzyl ester)

N-(N-benzyloxycarbonyl-L-seryl)-glycine ethyl ester

Downstream raw materials:

cyclo(glycyl-L-seryl)

4-methoxytrityl-Ser-Gly

serylglycine benzyl ester p-toluenesulfonate

4-chloro-phenol

Refernces

• 1、 BABA,SAKIYAMA,TITANI,NARITA. "THE SYNTHESIS OF N-TERMINAL ACETYLPEPTIDES OF OVALBUMIN AND MAMMALIAN". . p. 215 - 220. Retrieved 2007/10/06.