Myristoylcholine chloride

Base Information

• Chemical Name: Myristoylcholine chloride
• CAS No.: 4277-89-8
• Molecular Formula: C19H40 N O2 . Cl
• Molecular Weight: 349.985
• Hs Code.: 2923900090
• European Community (EC) Number: 224-282-1
• DSSTox Substance ID: DTXSID00962679
• Mol file: 4277-89-8.mol

Synonyms:Myristoylcholine chloride;4277-89-8;n,n,n-trimethyl-2-(tetradecanoyloxy)ethanaminium chloride;MYRISTOYL CHOLINE CHLORIDE;trimethyl(2-tetradecanoyloxyethyl)azanium;chloride;Trimethyl(2-myristoyloxyethyl)ammonium chloride;EINECS 224-282-1;C19H40NO2.Cl;MFCD00050186;SCHEMBL5266793;C19-H40-N-O2.Cl;DTXSID00962679;HY-W127482;CS-0185710;FT-0629058;Trimethyl-(2-Tetradecanoyloxyethyl)Azanium Chloride;n,n,n-trimethyl-2-(tetradecanoyloxy)ethanaminiumchloride;N,N,N-Trimethyl-2-(tetradecanoyloxy)ethan-1-aminium chloride;N,N,N-Trimethyl-2-[(1-oxotetradecyl)oxy]ethanaminium Chloride

Chemical Property of Myristoylcholine chloride

Chemical Property:

• Melting Point: 196 - 204°C (dec.)
• PSA: 26.30000
• LogP: 1.94090
• Storage Temp.: −20°C
• Solubility.: Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 16
• Exact Mass: 349.2747572
• Heavy Atom Count: 23
• Complexity: 259

Purity/Quality:

98%Min ^*data from raw suppliers

Myristoylcholine chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCC(=O)OCC[N+](C)(C)C.[Cl-]
• Uses: Myristoylcholine Chloride is a fatty acid choline ester with potential use as a skin penetration enhancer for drug delivery.

Technology Process of Myristoylcholine chloride

There total 3 articles about Myristoylcholine chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methylene chloride (74-87-3) + Myristinsaeure-2-(dimethylamino)ethylester (43016-78-0) → myristoyl choline chloride (4277-89-8)

Guidance literature:

In propylene glycol; at 80 ℃; under 2828.7 Torr; Inert atmosphere;

Reference yield:

n-tetradecanoic acid (544-63-8) → myristoyl choline chloride (4277-89-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 140 - 175 °C / Inert atmosphere

2: propylene glycol / 80 °C / 2828.7 Torr / Inert atmosphere

In propylene glycol;

Reference yield:

→ myristoyl choline chloride (4277-89-8)

Guidance literature:

CH3(CH2)12C(O)OCH2CH2Cl in DMF, N(CH3)3, 70-80grad, 20 h;

upstream raw materials:

n-tetradecanoic acid

methylene chloride

Myristinsaeure-2-(dimethylamino)ethylester

Downstream raw materials:

choline chloride

n-tetradecanoic acid

Refernces