Sarcosterol

Base Information

• Chemical Name: Sarcosterol
• CAS No.: 73731-24-5
• Molecular Formula: C₂₉H₄₈O
• Molecular Weight: 412.7
• Wikidata: Q76149916
• Metabolomics Workbench ID: 34859
• Mol file: 73731-24-5.mol

Synonyms:sarcosterol

Chemical Property of Sarcosterol

Chemical Property:

• Vapor Pressure: 3.37E-12mmHg at 25°C
• Boiling Point: 502.4°C at 760 mmHg
• Flash Point: 219.8°C
• Density: 0.99g/cm³
• XLogP3: 8.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 412.370516150
• Heavy Atom Count: 30
• Complexity: 714

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)C(C)C(C)CC(=C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C
• Isomeric SMILES: C[C@H](C/C(=C/1\CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)/C)[C@H](C)C(C)C

Technology Process of Sarcosterol

There total 5 articles about Sarcosterol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sarcosterol acetate → sarcosterol (73731-24-5)

Guidance literature:

With potassium hydroxide; In methanol; for 0.166667h; Yield given; Heating;

DOI:10.1016/0039-128X(94)90041-8

Reference yield:

(23R,24S)-23,24-dimethylcholesta-5,17(20)E-diene-3β,25-diol (153444-87-2) → sarcosterol (73731-24-5)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine / Ambient temperature

2: 11.5 mg / thionyl chloride / pyridine / 0.33 h / Ambient temperature

3: H₂, tris(triphenylphosphine)chlororhodium / benzene / 4 h / Ambient temperature

4: KOH / methanol / 0.17 h / Heating

With pyridine; potassium hydroxide; Wilkinson's catalyst; thionyl chloride; hydrogen; In pyridine; methanol; benzene;

DOI:10.1016/0039-128X(94)90041-8

Reference yield:

Acetic acid (3S,8R,9S,10R,13S,14S)-17-[(3R,4S)-5-hydroxy-1,3,4,5-tetramethyl-hex-(E)-ylidene]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester → sarcosterol (73731-24-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 11.5 mg / thionyl chloride / pyridine / 0.33 h / Ambient temperature

2: H₂, tris(triphenylphosphine)chlororhodium / benzene / 4 h / Ambient temperature

3: KOH / methanol / 0.17 h / Heating

With potassium hydroxide; Wilkinson's catalyst; thionyl chloride; hydrogen; In pyridine; methanol; benzene;

DOI:10.1016/0039-128X(94)90041-8

upstream raw materials:

(23R,24S)-23,24-dimethylcholesta-5,17(20)E-diene-3β,25-diol

Refernces