Diphenylmethane-2,2'-diisocyanate

Base Information

• Chemical Name: Diphenylmethane-2,2'-diisocyanate
• CAS No.: 2536-05-2
• Molecular Formula: C15H10 N2 O2
• Molecular Weight: 250.257
• European Community (EC) Number: 219-799-4
• UNII: AS00FWT3DM
• DSSTox Substance ID: DTXSID90883107
• Nikkaji Number: J192.024C
• Wikidata: Q27274092
• Mol file: 2536-05-2.mol

Synonyms:Diphenylmethane-2,2'-diisocyanate;2536-05-2;2,2'-Methylenediphenyl diisocyanate;1-isocyanato-2-[(2-isocyanatophenyl)methyl]benzene;AS00FWT3DM;bis(2-isocyanatophenyl)methane;DTXSID90883107;2,2'-methylenedi(phenyl isocyanate);Benzene, 1,1'-methylenebis(2-isocyanato-;1-isocyanato-2-((2-isocyanatophenyl)methyl)benzene;Bisphenol F diisocyanate;UNII-AS00FWT3DM;SCHEMBL15544;methylene-bis-phenylisocyanate;Methylene-diphenyl diisocyanate;2,2'-diisocyanatodiphenylmethane;EINECS 219-799-4;AKOS028110966;1,1'-Methylenebis(2-isocyanatobenzene);AS-62089;DIPHENYLMETHANE 2,2'-DIISOCYANATE;EC 219-799-4;EN300-22130347;ISOCYANIC ACID, METHYLENEDI-O-PHENYLENE ESTER;Q27274092

Chemical Property of Diphenylmethane-2,2'-diisocyanate

Chemical Property:

• Vapor Pressure: 5.92E-06mmHg at 25°C
• Boiling Point: 379.3°Cat760mmHg
• Flash Point: 156.5°C
• PSA: 58.86000
• Density: 1.13g/cm³
• LogP: 3.21200
• XLogP3: 5.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 250.074227566
• Heavy Atom Count: 19
• Complexity: 348

Purity/Quality:

99.9% ^*data from raw suppliers

1,1''-Methylenebis[2-isocyanatobenzene] ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)CC2=CC=CC=C2N=C=O)N=C=O
• Uses: 1,1''-Methylenebis[2-isocyanatobenzene] is an isoform of Methylene diphenyl diisocyanate used in the manufacture of polyurethane.

Technology Process of Diphenylmethane-2,2'-diisocyanate

There total 6 articles about Diphenylmethane-2,2'-diisocyanate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.1%

phosgene (75-44-5) + polyamines + 2,4'-diaminodiphenylmethane (1208-52-2) + 2,2'-methylenedianiline (6582-52-1) + 4,4'-diamino diphenyl methane (101-77-9) → polyisocyanates + 4,4′-methylenebis(phenylisocyanate) (2536-05-2) + 2,4'-diisocyanatodiphenylmethane (5873-54-1) + di(4-isocyanatophenyl)methane (101-68-8,25686-28-6,97568-33-7)

Guidance literature:

In chlorobenzene; at 0 ℃; Product distribution / selectivity;

Reference yield: 0.56%

→ 4,4′-methylenebis(phenylisocyanate) (2536-05-2) + 2,4'-diisocyanatodiphenylmethane (5873-54-1) + di(4-isocyanatophenyl)methane (101-68-8,25686-28-6,97568-33-7)

Guidance literature:

Product distribution / selectivity; Industry scale;

Reference yield:

phosgene (75-44-5) + 2,4'-diaminodiphenylmethane (1208-52-2) + 2,2'-methylenedianiline (6582-52-1) + 4,4'-diamino diphenyl methane (101-77-9) → 4,4′-methylenebis(phenylisocyanate) (2536-05-2) + 2,4'-diisocyanatodiphenylmethane (5873-54-1) + di(4-isocyanatophenyl)methane (101-68-8,25686-28-6,97568-33-7)

Guidance literature:

In chlorobenzene; at 0 ℃; Product distribution / selectivity; Heating / reflux;

upstream raw materials:

phosgene

formaldehyd

2,4'-diaminodiphenylmethane

2,2'-methylenedianiline

Downstream raw materials:

dibutyl diphenyl methane-4,4’-dicarbamate

Refernces

• 1、 -. "Process for the production of 4,4'-diphenylmethane diisocyanate". Page/Page column 3-4. . Retrieved 2008/06/13.
• 2、 -. "Process for distilling a mixture of isomeric diisocyanatodiphenylmethanes". Page/Page column 5-6. . Retrieved 2008/06/13.