Amiloride hydrochloride dihydrate

Base Information

• Chemical Name: Amiloride hydrochloride dihydrate
• CAS No.: 17440-83-4
• Molecular Formula: C6H13Cl2N7O3
• Molecular Weight: 302.12
• Hs Code.: 2933995300
• Mol file: 17440-83-4.mol

Synonyms:Pyrazinecarboxamide,3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride, dihydrate (9CI);Pyrazinecarboxamide, N-amidino-3,5-diamino-6-chloro-, monohydrochloride,dihydrate (8CI);N-Amidino-3,5-diamino-6-chloropyrazinamide hydrochloridedihydrate;2-Pyrazinecarboxamide,3,5-diamino-N-(aminoiminomethyl)-6-chloro-, hydrochloride, hydrate (1:1:2);

Chemical Property of Amiloride hydrochloride dihydrate

Chemical Property:

• Vapor Pressure: 1.08E-15mmHg at 25°C
• Melting Point: >240℃
• Boiling Point: 628.1 °C at 760 mmHg
• PKA: 8.7(at 25℃)
• Flash Point: 333.7 °C
• PSA: 175.25000
• LogP: 1.94440
• Solubility.: Slightly soluble in water and in anhydrous ethanol.
• Water Solubility.: Soluble in water at 50mg/ml

Purity/Quality:

99.9% ^*data from raw suppliers

Amiloride hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Amiloride hydrochloride dihydrate is used as a calcium channel and sodium channel protein inhibitor. It reduces electrical potential across tubular epithelium, inhibits angiogenesis and inhibits capillary morphogenesis completely and reversibly at approximately 130 ?M. Amiloride ? HCl is an inhibitor of Sodium/Potassium-ATPase Protein. Defines the I2A-amiloride sensitive and I2B-amiloride insensitive imidazoline binding Blocks TRPP3, acid sensing- (ASIC) and mechanogated membrane-ion channels, as well as the Na+/H+ exchanger. Also inhibits urokinase-type plasminogen activator (uPA); has no effect on tissue-type plasminogen activator. Diuretic;Antialdosteron An epithelial sodium channel blocker