9-Oxo-10(9H)-acridinebutanoic acid

Base Information

• Chemical Name: 9-Oxo-10(9H)-acridinebutanoic acid
• CAS No.: 90053-07-9
• Molecular Formula: C₁₇H₁₅NO₃
• Molecular Weight: 281.311
• Mol file: 90053-07-9.mol

Synonyms:4-(N-Acridonyl)butyricacid

Chemical Property of 9-Oxo-10(9H)-acridinebutanoic acid

Chemical Property:

• Vapor Pressure: 2.03E-11mmHg at 25°C
• Boiling Point: 514.7°Cat760mmHg
• Flash Point: 265.1°C
• PSA: 59.30000
• Density: 1.285g/cm³
• LogP: 3.01950

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9-Oxo-10(9H)-acridinebutanoic acid

There total 2 articles about 9-Oxo-10(9H)-acridinebutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethyl 4-(9-oxo-9,10-dihydro-10-acridinyl)butanoate (99081-83-1) → 4-(9-oxo-9,10-dihydro-10-acridinyl)butanoic acid (90053-07-9)

Guidance literature:

With sodium hydroxide; In ethanol; at 20 ℃;

DOI:10.1016/j.ejmech.2006.12.039

Reference yield:

10H-acridin-9-one (578-95-0,790240-54-9) → 4-(9-oxo-9,10-dihydro-10-acridinyl)butanoic acid (90053-07-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 17 percent / NaH; tetra-n-butylammonium iodide / dimethylformamide / 2 h / 80 °C

2: 100 percent / aq. NaOH / ethanol / 20 °C

With sodium hydroxide; tetra-(n-butyl)ammonium iodide; sodium hydride; In ethanol; N,N-dimethyl-formamide;

DOI:10.1016/j.ejmech.2006.12.039

upstream raw materials:

ethyl 4-(9-oxo-9,10-dihydro-10-acridinyl)butanoate

10H-acridin-9-one

Refernces