[(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 2-methylbutanoate;[(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate

Base Information

• Chemical Name: [(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 2-methylbutanoate;[(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate
• CAS No.: 642-15-9
• Molecular Formula: C28H40 N2 O9
• Molecular Weight: 548.62
• NSC Number: 723904
• Mol file: 642-15-9.mol

Synonyms:[(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 2-methylbutanoate;[(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate;NSC723904;NSC-723904

Chemical Property of [(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 2-methylbutanoate;[(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate

Chemical Property:

• Vapor Pressure: 4.41E-25mmHg at 25°C
• Melting Point: 149.5℃
• Refractive Index: 1.5800 (estimate)
• Boiling Point: 777.8°C at 760 mmHg
• Flash Point: 424.2°C
• PSA: 157.33000
• Density: 1.22g/cm³
• LogP: 4.58020
• Storage Temp.: −20°C
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 18
• Rotatable Bond Count: 24
• Exact Mass: 1096.54676172
• Heavy Atom Count: 78
• Complexity: 1700

Purity/Quality:

98%min ^*data from raw suppliers

AntimycinA1 ≥98.0% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 23/24/25
• Safety Statements: 36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCC1C(C(OC(=O)C(C(OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)CC(C)C.CCCCCCC1C(C(OC(=O)C(C(OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)C(C)CC
• Isomeric SMILES: CCCCCC[C@@H]1[C@H]([C@@H](OC(=O)[C@H]([C@H](OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)CC(C)C.CCCCCC[C@@H]1[C@H]([C@@H](OC(=O)[C@H]([C@H](OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)C(C)CC
• Description: Antimycin A1 is an active component of the antimycin A antibiotic complex. It inhibits electron transport and is active against the plant pathogenic fungus G. cingulate. Antimycin A1 (3.3-160 μM) induces the synthesis of carotenoids in M. marinum. It also inhibits ATP-citrate lyase (Ki = 29.5 μM).
• Uses: Antimycin A1 is the most hydrophobic of the four analogues of the antimycin A complex. Like all antimycins, antimycin A1 exhibits potent antifungal, anthelmintic, insecticidal, antiviral and antitumor activity across a range of bioassays. Although broadly active as respiration inhibitors, more recent investigation has highlighted the importance of individual members of the complex as bioprobes. Antimycin A1 inhibits angiogenesis via a decrease in VEGF production caused by inhibition of HIF-1a activation. Experimentally as fungicide, insecticide, miticide.