1,5-Bis(4-aminophenoxy)pentane

Base Information

• Chemical Name: 1,5-Bis(4-aminophenoxy)pentane
• CAS No.: 2391-56-2
• Molecular Formula: C17H22 N2 O2
• Molecular Weight: 286.374
• Hs Code.: 2922299090
• DSSTox Substance ID: DTXSID70178624
• Nikkaji Number: J516.347A
• Mol file: 2391-56-2.mol

Synonyms:1,5-bis(p-aminophenoxy)pentane;1,5-di(p-aminophenoxy)pentane;M and B 968A;M and B 968A dihydrochloride

Chemical Property of 1,5-Bis(4-aminophenoxy)pentane

Chemical Property:

• Vapor Pressure: 1.98E-08mmHg at 25°C
• Boiling Point: 510.1°Cat760mmHg
• Flash Point: 286.5°C
• PSA: 70.50000
• Density: g/cm³
• LogP: 4.64150
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 286.168127949
• Heavy Atom Count: 21
• Complexity: 234

Purity/Quality:

99.9% ^*data from raw suppliers

4,4'-(Pentane-1,5-diylbis(oxy))dianiline 95+% ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22
• Safety Statements: 36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1N)OCCCCCOC2=CC=C(C=C2)N

Technology Process of 1,5-Bis(4-aminophenoxy)pentane

There total 15 articles about 1,5-Bis(4-aminophenoxy)pentane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

1,5-bis-(4-acetylamino-phenoxy)-pentane (104209-30-5) → 1,5-bis(4-aminophenoxy)pentane (2391-56-2)

Guidance literature:

With sodium hydroxide; In ethanol; Heating;

DOI:10.1039/b104490g

Reference yield: 58.0%

1,5-Bis(4-nitrophenoxy)pentane (14467-60-8) → 1,5-bis(4-aminophenoxy)pentane (2391-56-2)

Guidance literature:

With hydrogen; palladium on activated charcoal;

DOI:10.1016/0223-5234(92)90114-G

Reference yield:

1,5-dibromo-pentane (111-24-0) → 1,5-bis(4-aminophenoxy)pentane (2391-56-2)

Guidance literature:

Multi-step reaction with 2 steps

1: dimethylformamide / 10 h / Heating

2: H₂ / 5percent Pd/C / tetrahydrofuran; methanol / 2280 Torr

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;

DOI:10.1021/jm00149a032

upstream raw materials:

1,5-Bis(4-nitrophenoxy)pentane

4,4'-pentanediyldioxy-di-aniline; dihydrochloride

1,5-bis-(4-acetylamino-phenoxy)-pentane

1,5-dibromo-pentane

Downstream raw materials:

1,5-bis-(4-[2]pyridylamino-phenoxy)-pentane

1,5-bis-(4-piperidino-phenoxy)-pentane

N,N'-diisopropyl-4,4'-pentanediyldioxy-di-aniline

N,N'-Bis(dimethylaminomethylen)-4,4'-pentamethylendioxydianilin-dihydrochlorid

Refernces

• 1、 Shakil, Maria,Akhter, Toheed,Siddiqi, Humaira Masood,Akhtar, Zareen. "The effect of even-odd methylene spacer groups on the thermal stability of epoxy-amine polymers". . p. 92 - 98. Retrieved 2015/05/20.
• 2、 Tyagi, Vikas,Khan, Shahnawaz,Shivahare, Rahul,Srivastava, Khushboo,Gupta, Suman,Kidwai, Saqib,Srivastava, Kumkum,Puri,Chauhan, Prem M.S.. "A natural product inspired hybrid approach towards the synthesis of novel pentamidine based scaffolds as potential anti-parasitic agents". supporting information. p. 291 - 296. Retrieved 2013/02/23.