1,3-Benzodioxole-5-acetic acid

Base Information Edit

Chemical Name:1,3-Benzodioxole-5-acetic acid
CAS No.:2861-28-1
Molecular Formula:C9H8O4
Molecular Weight:180.16
Hs Code.:29163990
European Community (EC) Number:220-679-9
NSC Number:14364
UNII:V73F6586V4
DSSTox Substance ID:DTXSID80182792
Nikkaji Number:J13.730H
Wikidata:Q63398279
Mol file:2861-28-1.mol

Synonyms:2861-28-1;3,4-(Methylenedioxy)phenylacetic acid;1,3-Benzodioxole-5-acetic acid;2-(Benzo[d][1,3]dioxol-5-yl)acetic acid;3,4-Methylenedioxyphenylacetic acid;Homopiperonylic acid;2-(1,3-benzodioxol-5-yl)acetic acid;(1,3-Benzodioxol-5-yl)acetic Acid;Benzo-1,3-dioxole-5-acetic acid;MFCD00014576;1,3-Benzodioxol-5-ylacetic acid;AI3-19940;2-(2H-1,3-Benzodioxol-5-Yl)Acetic Acid;3,4-Methylendioxyphenylacetic acid;EINECS 220-679-9;NSC-14364;2-(1,3-dioxaindan-5-yl)acetic acid;2-(3,4-methylenedioxyphenyl)acetic acid;benzo(1,3)dioxol-5-yl-acetic acid;Benzo[1,3]dioxol-5-yl-acetic acid;Benzo-[1,3]-dioxole-yl-5-acetic acid;Oprea1_381545;SCHEMBL138875;(Benzodioxol-5-yl)acetic acid;DTXSID80182792;BDBM231633;HMS1664D10;5-Carboxymethyl-1,3-benzodioxolane;NSC14364;(1,3-Benzodioxol-5-yl)acetic aci;1,3-Benzodioxol-5-ylacetic acid #;3,4(methylenedioxy)phenylacetic acid;3,4-methylenedioxyphenyl acetic acid;NSC 14364;STL553768;(3,4-methylenedioxy)phenylacetic acid;(3,4-methylenedioxyphenyl)acetic acid;AKOS000295881;2-benzo[1,3]dioxol-5-yl-acetic acid;AC-9153;AM84883;Benzo[1,3]-dioxole-yl-5-acetic acid;CS-W007484;PS-5821;V73F6586V4;3,4-(methylenedioxy) phenylacetic acid;2-(1,3-benzodioxol-5-yl)-acetic acid;2-(3,4-methylenedioxy)phenylacetic acid;2-(benzo[1,3]dioxol-5-yl)acetic acid;BP-12600;SY003004;2-(benzo[1,3]dioxol-5-yl)-acetic acid;3,4-(Methylenedioxy)benzene-1-acetic acid;3,4-(Methylenedioxy)phenylacetic acid, 98%;Acetic acid, [3,4-(methylenedioxy)phenyl]-;FT-0614404;M1008;2-(benzo[d][1,3]dioxol-5-yl)-acetic acid;EN300-52290;AP-065/41718246;J-511101;Q63398279;F2191-0046;Z274782846

Suppliers and Price of 1,3-Benzodioxole-5-acetic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,4-Methylenedioxyphenylacetic Acid
1g
$ 110.00

TCI Chemical
3,4-Methylenedioxyphenylacetic Acid >98.0%(GC)(T)
5g
$ 140.00

TCI Chemical
3,4-Methylenedioxyphenylacetic Acid >98.0%(GC)(T)
25g
$ 562.00

SynQuest Laboratories
(1,3-Benzodioxol-5-yl)aceticacid 98.0%
250 g
$ 672.00

SynQuest Laboratories
(1,3-Benzodioxol-5-yl)aceticacid 98.0%
100 g
$ 336.00

SynQuest Laboratories
(1,3-Benzodioxol-5-yl)aceticacid 98.0%
25 g
$ 112.00

Sigma-Aldrich
3,4-(Methylenedioxy)phenylacetic acid 98%
5g
$ 104.00

Matrix Scientific
3,4-Methylenedioxyphenylacetic acid 98%
5g
$ 48.00

Matrix Scientific
3,4-Methylenedioxyphenylacetic acid 98%
25g
$ 216.00

Labseeker
3,4-Methylenedioxyphenylacetic Acid 98
25g
$ 333.00

Total 74 raw suppliers

Chemical Property of 1,3-Benzodioxole-5-acetic acid Edit

Chemical Property:

Appearance/Colour:beige to pale yellow micro-crystalline powder
Vapor Pressure:3.29E-05mmHg at 25°C
Melting Point:125-129 °C(lit.)
Refractive Index:1.4500 (estimate)
Boiling Point:340.6 °C at 760 mmHg
PKA:4.31±0.10(Predicted)
Flash Point:142.4 °C
PSA：55.76000
Density:1.407 g/cm³
LogP:1.04240
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:DMSO (Slightly), Methanol (Slightly)
Water Solubility.:Soluble in water (partly), ethanol, and methanol.
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:180.04225873
Heavy Atom Count:13
Complexity:204

Purity/Quality:

98% ^*data from raw suppliers

3,4-Methylenedioxyphenylacetic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1OC2=C(O1)C=C(C=C2)CC(=O)O
Uses 3,4-(Methylenedioxy)phenylacetic acid is used as organic intermediates.

Technology Process of 1,3-Benzodioxole-5-acetic acid

There total 31 articles about 1,3-Benzodioxole-5-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 4439-02-5
3,4-methylenedioxyphenylacetonitrile

: 2861-28-1
1,3-benzodioxole-5-acetic acid

Guidance literature:: With sodium hydroxide; In methanol;
DOI:10.1016/S0040-4039(99)02328-X

Reference yield: 99.0%

: 326-59-0
benzo[1,3]dioxol-5-yl-acetic acid methyl ester

: 2861-28-1
1,3-benzodioxole-5-acetic acid

Guidance literature:: benzo[1,3]dioxol-5-yl-acetic acid methyl ester; With potassium hydroxide; water; In methanol; for 3h; Heating / reflux;

With hydrogenchloride; In water; pH=1;

Reference yield: 98.4%

: 27738-46-1
3,4-(methylenedioxy)mandelic acid

: 2861-28-1
1,3-benzodioxole-5-acetic acid

Guidance literature:: With phosphonic Acid; methanesulfonic acid; sodium iodide; In water; at 40 ℃; for 48h; Inert atmosphere;
DOI:10.1021/jo2018087