endo-1,5,5-Trimethylbicyclo(2.2.1)heptan-2-ol

Base Information

• Chemical Name: endo-1,5,5-Trimethylbicyclo(2.2.1)heptan-2-ol
• CAS No.: 534-35-0
• Molecular Formula: C₁₀H₁₈O
• Molecular Weight: 154.252
• European Community (EC) Number: 208-599-2
• DSSTox Substance ID: DTXSID301204420
• Nikkaji Number: J2.934.505H
• Mol file: 534-35-0.mol

Synonyms:534-35-0;endo-1,5,5-Trimethylbicyclo(2.2.1)heptan-2-ol;EINECS 208-599-2;endo-1,5,5-trimethylbicyclo[2.2.1]heptan-2-ol;Bicyclo(2.2.1)heptan-2-ol, 1,5,5-trimethyl-, endo-;Bicyclo[2.2.1]heptan-2-ol, 1,5,5-trimethyl-, endo-;DTXSID301204420;(1R,2R,4R)-1,5,5-Trimethylbicyclo[2.2.1]heptane-2-ol;rel-(1R,2R,4R)-1,5,5-Trimethylbicyclo[2.2.1]heptan-2-ol

Chemical Property of endo-1,5,5-Trimethylbicyclo(2.2.1)heptan-2-ol

Chemical Property:

• Vapor Pressure: 0.0693mmHg at 25°C
• Boiling Point: 202.9°Cat760mmHg
• PKA: 15.35±0.60(Predicted)
• Flash Point: 80.7°C
• PSA: 20.23000
• Density: 0.992g/cm³
• LogP: 2.19350
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 154.135765193
• Heavy Atom Count: 11
• Complexity: 185

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(CC2(CC1CC2O)C)C
• Isomeric SMILES: C[C@]12C[C@H](C[C@H]1O)C(C2)(C)C

Technology Process of endo-1,5,5-Trimethylbicyclo(2.2.1)heptan-2-ol

There total 18 articles about endo-1,5,5-Trimethylbicyclo(2.2.1)heptan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-endo-Bromo-1.5.5-trimethyl-2-endo-norbornanol → (1R)-1,5,5-trimethyl-norbornane-2endo-ol (534-34-9,534-35-0,6168-62-3,71686-38-9,71686-39-0,95839-58-0,111821-62-6)

Guidance literature:

With zinc; In ethanol; Heating;

DOI:10.1039/jr9640005254

Reference yield:

6-endo-Bromo-1,5,5-trimethylnorbornan-2-on (3899-12-5,23287-10-7) → (1R)-1,5,5-trimethyl-norbornane-2endo-ol (534-34-9,534-35-0,6168-62-3,71686-38-9,71686-39-0,95839-58-0,111821-62-6)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄

2: Zn / ethanol / Heating

With sodium tetrahydroborate; zinc; In ethanol;

DOI:10.1039/jr9640005254

Reference yield:

6,6-dimethyl-2-methylene-bicyclo[3.1.1]heptan-3-ol (19894-98-5) → (1R)-1,5,5-trimethyl-norbornane-2endo-ol (534-34-9,534-35-0,6168-62-3,71686-38-9,71686-39-0,95839-58-0,111821-62-6)

Guidance literature:

Multi-step reaction with 4 steps

1: HBr

2: CrO₃, Py

3: NaBH₄

4: Zn / ethanol / Heating

With pyridine; chromium(VI) oxide; sodium tetrahydroborate; hydrogen bromide; zinc; In ethanol;

DOI:10.1039/jr9640005254

upstream raw materials:

aluminum isopropoxide

isofenchone

isopropyl alcohol

ethanol

Downstream raw materials:

(+/-)-O-(2-Carboxy-benzoyl)-β-isofenchol

(+/-)-6endo-Acetoxy-1.3.3-trimethyl-norbornan

phthalic acid mono-((1S)-1.5.5-trimethyl-norbornyl-(2endo)-ester)