1,3-Dimethyl-2-quinoxalinone

Base Information

• Chemical Name: 1,3-Dimethyl-2-quinoxalinone
• CAS No.: 3149-25-5
• Molecular Formula: C10H10N2O
• Molecular Weight: 174.202
• Hs Code.: 2933990090
• Mol file: 3149-25-5.mol

Synonyms:1,3-Dimethyl-1H-quinoxalin-2-one;1,3-Dimethyl-2(1H)-quinoxalin-2-one;1,3-Dimethyl-2(1H)-quinoxalone;1,3-Dimethyl-2-quinoxalinone;NSC 521683;

Chemical Property of 1,3-Dimethyl-2-quinoxalinone

Chemical Property:

• Vapor Pressure: 0.000957mmHg at 25°C
• Melting Point: 86-87 °C
• Refractive Index: 1.608
• Boiling Point: 303 °C at 760 mmHg
• PKA: 0.21±0.70(Predicted)
• Flash Point: 137 °C
• PSA: 34.89000
• Density: 1.18 g/cm³
• LogP: 1.24190

Purity/Quality:

99% ^*data from raw suppliers

1,3-Dimethylquinoxalin-2(1H)-one 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-Dimethyl-2-quinoxalinone

There total 1 articles about 1,3-Dimethyl-2-quinoxalinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

2-azido-N-(2-iodophenyl)-N-methylpropanamide (1029963-81-2) → 1,3-dimethyl-1H-quinoxalin-2-one (3149-25-5) + N-methyl-N-phenylformamide (93-61-8)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; at 80 ℃;

DOI:10.1021/jo800453z

Reference yield: 90.0%

1,3-dimethyl-1H-quinoxalin-2-one (3149-25-5) + 4-bromo-benzaldehyde (1122-91-4) → 3-[(E)-2-(4-Bromo-phenyl)-vinyl]-1-methyl-1H-quinoxalin-2-one (93585-07-0)

Guidance literature:

With piperidine; for 0.166667h;

DOI:10.1246/bcsj.57.1653

Reference yield: 86.0%

4-vinylpyridine (100-43-6,329041-72-7) + 1,3-dimethyl-1H-quinoxalin-2-one (3149-25-5) → 2a,4-Dimethyl-1-pyridin-4-yl-2,2a-dihydro-1H,4H-azeto[1,2-a]quinoxalin-3-one (112828-60-1)

Guidance literature:

In benzene; for 15h; Ambient temperature; Irradiation;

upstream raw materials:

2-azido-N-(2-iodophenyl)-N-methylpropanamide

Downstream raw materials:

NSC86927

1-methyl-3-(4-dimethylaminostyryl)-1,4-benzodiazine-2-one

2a,4-Dimethyl-1-pyridin-4-yl-2,2a-dihydro-1H,4H-azeto[1,2-a]quinoxalin-3-one

2a,4-Dimethyl-1-phenyl-2,2a-dihydro-1H,4H-azeto[1,2-a]quinoxalin-3-one

Refernces