Technology Process of (6,7-dimethoxyisoquinolin-1-yl)(4,5-dimethoxy-2-nitrophenyl)methanone
There total 11 articles about (6,7-dimethoxyisoquinolin-1-yl)(4,5-dimethoxy-2-nitrophenyl)methanone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
oxygen; 1,8-diazabicyclo[5.4.0]undec-7-ene; copper(ll) bromide;
In
dimethyl sulfoxide;
at 35 ℃;
for 8h;
Green chemistry;
DOI:10.1039/c8ra05338c
- Guidance literature:
-
Multi-step reaction with 2 steps
1: trichlorophosphate / acetonitrile / 2 h / Reflux
2: 1,8-diazabicyclo[5.4.0]undec-7-ene; copper(ll) bromide; oxygen / dimethyl sulfoxide / 8 h / 35 °C / Green chemistry
With
oxygen; 1,8-diazabicyclo[5.4.0]undec-7-ene; copper(ll) bromide; trichlorophosphate;
In
dimethyl sulfoxide; acetonitrile;
1: |Bischler-Napieralski Reaction;
DOI:10.1039/c8ra05338c
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: ethylenediamine / 5 h / Reflux
2.1: lithium aluminium tetrahydride / tetrahydrofuran / Reflux
3.1: potassium carbonate / dichloromethane; water / 0 - 5 °C
3.2: 2 h / 0 - 5 °C
4.1: trichlorophosphate / acetonitrile / 2 h / Reflux
5.1: 1,8-diazabicyclo[5.4.0]undec-7-ene; copper(ll) bromide; oxygen / dimethyl sulfoxide / 8 h / 35 °C / Green chemistry
With
lithium aluminium tetrahydride; oxygen; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; ethylenediamine; copper(ll) bromide; trichlorophosphate;
In
tetrahydrofuran; dichloromethane; water; dimethyl sulfoxide; acetonitrile;
4.1: |Bischler-Napieralski Reaction;
DOI:10.1039/c8ra05338c