(4-(Methoxycarbonyl)benzyl)triphenylphosphonium chloride

Base Information

• Chemical Name: (4-(Methoxycarbonyl)benzyl)triphenylphosphonium chloride
• CAS No.: 1253-47-0
• Molecular Formula: C27H24 O2 P . Cl
• Molecular Weight: 446.913
• Hs Code.: 2931900090
• European Community (EC) Number: 681-196-0
• DSSTox Substance ID: DTXSID50592389
• NSC Number: 64107
• Mol file: 1253-47-0.mol

Synonyms:1253-47-0;(4-(Methoxycarbonyl)benzyl)triphenylphosphonium chloride;4-CARBOMETHOXYBENZYL TRIPHENYLPHOSPHONIUM CHLORIDE;4-Methoxycarbonyl-benzyltriphenylphosphoniumchloride;(4-Methoxycarbonylbenzyl)triphenylphosphonium chloride;(4-methoxycarbonylphenyl)methyl-triphenylphosphanium;chloride;Phosphonium, [[4-(methoxycarbonyl)phenyl]methyl]triphenyl-, chloride (1:1);4-Methoxycarbonyl-benzyltriphenylphosphonium chloride;SCHEMBL1509558;DTXSID50592389;NSC64107;MFCD02683069;NSC 64107;NSC-64107;AKOS024389671;AM84363;CS-0529676;E80219;J-005217;(4-(Methoxycarbonyl)benzyl)triphenylphosphoniumchloride;(4-Methoxycarbonyl-benzyl)-triphenyl-phosphonium chloride;(4-methoxycarbonylphenyl)methyl triphenylphosphonium chloride;{[4-(Methoxycarbonyl)phenyl]methyl}(triphenyl)phosphanium chloride;{[4-(METHOXYCARBONYL)PHENYL]METHYL}TRIPHENYLPHOSPHANIUM CHLORIDE

Chemical Property of (4-(Methoxycarbonyl)benzyl)triphenylphosphonium chloride

Chemical Property:

• Melting Point: 258-260°C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 39.89000
• Density: g/cm³
• LogP: 1.97130
• Sensitive.: Hygroscopic
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 446.1202447
• Heavy Atom Count: 31
• Complexity: 475

Purity/Quality:

99% ^*data from raw suppliers

(4-METHOXYCARBONYLBENZYL)TRIPHENYLPHOSPHONIUM CHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C1=CC=C(C=C1)C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[Cl-]

Technology Process of (4-(Methoxycarbonyl)benzyl)triphenylphosphonium chloride

There total 1 articles about (4-(Methoxycarbonyl)benzyl)triphenylphosphonium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-methyloxycarbonylbenzyl chloride (34040-64-7) + triphenylphosphine (603-35-0) → triphenyl-(4-methoxycarbonylbenzyl)phosphonium chloride (1253-47-0)

Guidance literature:

DOI:10.1021/jo01091a022

Reference yield: 89.0%

triphenyl-(4-methoxycarbonylbenzyl)phosphonium chloride (1253-47-0) + salicylaldehyde (90-02-8) → 4-[(E)-2-(2-Hydroxy-phenyl)-vinyl]-benzoic acid methyl ester (110983-40-9,72398-90-4)

Guidance literature:

With potassium hydroxide; In PEG-600; at 20 ℃; for 12h;

DOI:10.1039/c2gc16181h

Reference yield: 77.0%

(4R,5R)-2,2-dimethyl-4-(3-oxopropyl)-5-phenyl-3-oxazolidinecarboxylic acid 1,1-dimethylethyl ester (1190391-88-8) + triphenyl-(4-methoxycarbonylbenzyl)phosphonium chloride (1253-47-0) → tert-butyl (4R,5R)-4-{4-[4-(methoxycarbonyl)phenyl]but-3-en-1-yl}-2,2-dimethyl-5-phenyl-1,3-oxazolidine-3-carboxylate (1269429-02-8)

Guidance literature:

triphenyl-(4-methoxycarbonylbenzyl)phosphonium chloride; With sodium t-butanolate; In dimethyl sulfoxide; at 20 ℃; for 0.75h;

(4R,5R)-2,2-dimethyl-4-(3-oxopropyl)-5-phenyl-3-oxazolidinecarboxylic acid 1,1-dimethylethyl ester; In dimethyl sulfoxide; at 20 ℃; for 1.5h;

upstream raw materials:

p-methyloxycarbonylbenzyl chloride

triphenylphosphine

Downstream raw materials:

4-(4t-phenyl-buta-1,3-dien-ξ-yl)-benzoic acid methyl ester

methyl 4-[(E)-2-(4-(E)-2-[4-methoxycarbonylphenyl]ethenylphenyl)ethenyl]benzoate

tert-butyl (2S,4R)-4-(((4-chlorophenyl)sulfonyl)amino)-2-((Z)-2-(4-(methoxycarbonyl)phenyl)ethenyl)-1-pyrrolidinecarboxylate

tert-butyl (2S,4R)-4-(((4-chlorophenyl)sulfonyl)amino)-2-((E)-2-(4-(methoxycarbonyl)phenyl)ethenyl)-1-pyrrolidinecarboxylate