15-Oxo-9-hydroxykaur-16-en-18-oic acid

Base Information

• Chemical Name: 15-Oxo-9-hydroxykaur-16-en-18-oic acid
• CAS No.: 77658-39-0
• Molecular Formula: C₂₀H₂₈O₄
• Molecular Weight: 332.44
• Mol file: 77658-39-0.mol

Synonyms:9-hydroxy-15-oxo-ent-kaur-16-en-19-oic acid;

Chemical Property of 15-Oxo-9-hydroxykaur-16-en-18-oic acid

Chemical Property:

• Boiling Point: 509.9±50.0 °C(Predicted)
• PKA: 4.56±0.60(Predicted)
• PSA: 74.60000
• Density: 1.23±0.1 g/cm3(Predicted)
• LogP: 3.33400

Purity/Quality:

98%min ^*data from raw suppliers

ent-9-Hydroxy-15-oxokaur-16-en-19-oicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 15-Oxo-9-hydroxykaur-16-en-18-oic acid

There total 2 articles about 15-Oxo-9-hydroxykaur-16-en-18-oic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

9-hydroxy-15-oxo-ent-kaur-16-en-19-oyl-β-D-glucoside (81263-96-9) → ent-9-hydroxy-15-oxo-kaur-16-en-19-saeure (77658-39-0)

Guidance literature:

With hesperidinase; at 40 ℃; for 3h; pH=4.0 citrate buffer;

DOI:10.1248/cpb.29.3455

Reference yield:

ent-9,15α-dihydroxy-kaur-16-en-19-saeure (77533-70-1,93888-87-0) → ent-9-hydroxy-15-oxo-kaur-16-en-19-saeure (77658-39-0)

Guidance literature:

With jones reagent; In acetone; for 0.5h; Yield given;

DOI:10.1248/cpb.29.657

Reference yield:

ent-9-hydroxy-15-oxo-kaur-16-en-19-saeure (77658-39-0) → C20H30O4 (77658-45-8)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol; for 3h; Yield given;

DOI:10.1248/cpb.29.657

upstream raw materials:

9-hydroxy-15-oxo-ent-kaur-16-en-19-oyl-β-D-glucoside

ent-9,15α-dihydroxy-kaur-16-en-19-saeure

Downstream raw materials:

C₂₀H₃₀O₄

Refernces

• 1、 Murakami,Iida,Tanaka,et al.. "Chemical and chemotaxonomic studies on ferns. XXXIII. Chemical analysis of Pteris longipesDon.". . p. 657 - 662. Retrieved 2007/10/02.