DESMETHYLBELLIDIFOLIN

Base Information

• Chemical Name: DESMETHYLBELLIDIFOLIN
• CAS No.: 2980-32-7
• Molecular Formula: C13H8 O6
• Molecular Weight: 260.203
• Mol file: 2980-32-7.mol

Synonyms:Xanthen-9-one,1,3,5,8-tetrahydroxy- (6CI,7CI,8CI); 1,3,5,8-Tetrahydroxyxanthen-9-one;1,3,5,8-Tetrahydroxyxanthone; 3-O-Demethylbellidifolin; Bellidin;Demethylbellidifolin; Desmethylbellidifolin; Desmethylbellidifoline;Norbellidifodin

Chemical Property of DESMETHYLBELLIDIFOLIN

Chemical Property:

• Vapor Pressure: 2.93E-15mmHg at 25°C
• Melting Point: 317oC
• Boiling Point: 605.6oC at 760 mmHg
• PKA: 6.54±0.20(Predicted)
• Flash Point: 241.9oC
• Density: 1.766g/cm3

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,3,5,8-Tetrahydroxyxanthone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1,3,5,8-Tetrahydroxy-9H-xanthen-9-one is an α-glucosidase inhibitor.

Technology Process of DESMETHYLBELLIDIFOLIN

There total 22 articles about DESMETHYLBELLIDIFOLIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

5,8-dihydroxy-1,3-dimethoxy-9H-xanthen-9-one (103726-10-9) → 1,3,5,8-tetrahydroxyxanthone (2980-32-7)

Guidance literature:

With aluminium trichloride; In benzene; for 4h; Heating;

DOI:10.1002/hlca.19850680832

Reference yield: 50.0%

1,3,8-trihydroxyxanthone (6052-93-3) → 1,3,5,8-tetrahydroxyxanthone (2980-32-7)

Guidance literature:

With pyridine; dipotassium peroxodisulfate; potassium hydroxide; In water; at 20 ℃; for 21h;

Reference yield:

C48H38O18 → bellidin 8-O-β-glucopyranoside (54954-12-0,26107-89-1) + 1,3,5,8-tetrahydroxyxanthone (2980-32-7)

Guidance literature:

With sodium methylate; In methanol; pH 10;

DOI:10.1002/hlca.19850680832

upstream raw materials:

bellidifolin

1,3,8-trihydroxy-5-methoxy-9H-xanthen-9-one

methylbellidifolin

1,3,5,8-tetramethoxy-9H-xanthen-9-one

Downstream raw materials:

bellidifolin

1,3,5-tribenzoyloxy-8-hydroxy-9H-xanthen-9-one

5-benzyloxy-3,8-dihydroxy-1-methoxy-9H-xanthen-9-one

bellidin 8-O-β-glucopyranoside

Refernces

• 1、 Markham. "-". . . Retrieved 1965.
• 2、 -. "A bellidifodin preparing method". . . Retrieved 2017/05/10.