1,5-Bis(di-2-pyridylmethylene)thiocarbonohydrazide

Base Information

• Chemical Name: 1,5-Bis(di-2-pyridylmethylene)thiocarbonohydrazide
• CAS No.: 85191-43-1
• Molecular Formula: C23H18N8S
• Molecular Weight: 438.516
• DSSTox Substance ID: DTXSID60234389
• Nikkaji Number: J227.874J
• Mol file: 85191-43-1.mol

Synonyms:1,5-bis(di-2-pyridylmethylene)thiocarbonohydrazide;DPTH

Chemical Property of 1,5-Bis(di-2-pyridylmethylene)thiocarbonohydrazide

Chemical Property:

• Boiling Point: 656.6oC at 760 mmHg
• Flash Point: 350.9oC
• PSA: 139.47000
• Density: 1.3g/cm3
• LogP: 3.73790
• XLogP3: 4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 6
• Exact Mass: 438.13751378
• Heavy Atom Count: 32
• Complexity: 572

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=NC(=C1)C(=NNC(=S)NN=C(C2=CC=CC=N2)C3=CC=CC=N3)C4=CC=CC=N4

Technology Process of 1,5-Bis(di-2-pyridylmethylene)thiocarbonohydrazide

There total 1 articles about 1,5-Bis(di-2-pyridylmethylene)thiocarbonohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2'-dipyridyl ketone (19437-26-4) + Thiocarbohydrazide (2231-57-4) → 1,5-bis(di-2-pyridyl ketone)thiocarbohydrazone (85191-43-1)

Guidance literature:

In methanol; Heating;

DOI:10.1039/a607689k

Reference yield: 93.4%

copper(II) choride dihydrate + 1,5-bis(di-2-pyridyl ketone)thiocarbohydrazone (85191-43-1) → [Cu3(1,5-bis(di-2-pyridyl ketone)thiocarbohydrazone(-1H))(1,5-bis(di-2-pyridyl ketone)thiocarbohydrazone(-2H))Cl3]*3H2O

Guidance literature:

In methanol; ligand in hot MeOH mixed with Cu salt (molar ratio 1:1) in MeOH; refluxed for 10 min; filtered; ppt. washed with MeOH and ether; dried in vac. over P4O10; elem. anal.;

DOI:10.1016/j.saa.2008.10.030

Reference yield: 63.0%

ammonium hexafluorophosphate + nickel(II) chloride hexahydrate + 1,5-bis(di-2-pyridyl ketone)thiocarbohydrazone (85191-43-1) → [Ni4(bis(di-2-pyridyl ketone)thiocarbohydrazonate)4](PF6)4*11H2O

Guidance literature:

In methanol; 1 equiv. of Ni-salt in hot MeOH was added to hot MeOH soln. of the S-compd., reflux for an hour, 2 equiv. of NH4PF6 was added in MeOH, reflux for 2 h; soln. was allowed to stand at room temp., ppt. was filtered off, washed with MeOH and ether, recrystn. from MeCN/ethanol (1:1), dried in vac., elem. anal.;

DOI:10.1016/j.poly.2007.05.048

upstream raw materials:

2,2'-dipyridyl ketone

Thiocarbohydrazide

Refernces