4,5-Dichloro-2-methoxyaniline

Base Information

• Chemical Name: 4,5-Dichloro-2-methoxyaniline
• CAS No.: 60468-21-5
• Molecular Formula: C7H7Cl2NO
• Molecular Weight: 192.045
• European Community (EC) Number: 875-507-0
• DSSTox Substance ID: DTXSID80209211
• Wikidata: Q83083417
• Mol file: 60468-21-5.mol

Synonyms:4,5-dichloro-2-methoxyaniline;60468-21-5;2-methoxy-4,5-dichloroaniline;Benzenamine, 4,5-dichloro-2-methoxy-;SCHEMBL9416808;DTXSID80209211;OMUPQCXITFAUCB-UHFFFAOYSA-N;MFCD20690635;AKOS017529725;BS-42584;EN300-176137;F10963;A868974;Z1262622013

Chemical Property of 4,5-Dichloro-2-methoxyaniline

Chemical Property:

• Vapor Pressure: 0.00114mmHg at 25°C
• Melting Point: 88 °C
• Boiling Point: 300.1°C at 760 mmHg
• PKA: 2.84±0.10(Predicted)
• Flash Point: 135.3°C
• PSA: 35.25000
• Density: 1.375g/cm³
• LogP: 3.16540
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 190.9904692
• Heavy Atom Count: 11
• Complexity: 134

Purity/Quality:

95+% ^*data from raw suppliers

4,5-Dichloro-2-methoxyaniline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C=C1N)Cl)Cl

Technology Process of 4,5-Dichloro-2-methoxyaniline

There total 4 articles about 4,5-Dichloro-2-methoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2-dichloro-4-methoxy-5-nitrobenzene (100948-84-3) → 2-methoxy-4,5-dichloroaniline (60468-21-5)

Guidance literature:

With hydrogenchloride; tin;

Reference yield:

N-(2-methoxyphenyl)methanesulfonamide (7022-25-5) → 2-methoxy-4,5-dichloroaniline (60468-21-5)

Guidance literature:

Multi-step reaction with 2 steps

1: chlorine

With chlorine;

Reference yield:

→ 2-methoxy-4,5-dichloroaniline (60468-21-5)

Guidance literature:

4,5-Dichlor-2-methoxy-N--anilin, konz. H2SO4;

DOI:10.1039/jr9600000769

upstream raw materials:

1,2-dichloro-4-methoxy-5-nitrobenzene

N-(2-methoxyphenyl)methanesulfonamide

Downstream raw materials:

3-hydroxy-[2]-naphthoic acid-(4,5-dichloro-2-methoxy-anilide)

C₁₅H₁₄Cl₂N₂O₄S

5-chloro-2-methoxyaniline

4,5-dichloro-2-methoxyacetanilide

Refernces

• 1、 -. "Synergistic plant growth regulator compositions". . . Retrieved 2008/06/13.
• 2、 -. "Unsymmetrical 1:2-chromium complexes containing an azo compound and an azomethine compound". . . Retrieved 2008/06/13.