2-Arachidonoylglycerol

Base Information Edit

Chemical Name:2-Arachidonoylglycerol
CAS No.:53847-30-6
Molecular Formula:C23H38O4
Molecular Weight:378.552
Hs Code.:2916190090
UNII:8D239QDW64
ChEMBL ID:CHEMBL122972
DSSTox Substance ID:DTXSID001017454
Metabolomics Workbench ID:5773
Nikkaji Number:J671.147B
Pharos Ligand ID:CQT2W1D3R2NU
Wikidata:Q209320
Wikipedia:2-Arachidonoylglycerol
Mol file:53847-30-6.mol

Synonyms:2-arachidonoyl-glycerol;2-arachidonoylglycerol;2-arachidonyl-glycerol;2-arachidonylglycerol;2-monoarachidonoylglycerol;5,8,11,14-eicosatetraenoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (all-Z)-;glyceryl 2-arachidonate

Suppliers and Price of 2-Arachidonoylglycerol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Tocris
2-Arachidonyl glycerol
10
$ 207.00

Sigma-Aldrich
2-Arachidonyl glycerol ~10 mg/mL, ≥98% (HPLC)
5mg
$ 333.00

Cayman Chemical
2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG)
10mg
$ 163.00

Cayman Chemical
2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG)
5mg
$ 108.00

Cayman Chemical
2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG)
1mg
$ 28.00

Cayman Chemical
2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG)
25mg
$ 305.00

American Custom Chemicals Corporation
2-ARACHIDONYL GLYCEROL 95.00%
5MG
$ 503.92

Total 50 raw suppliers

Chemical Property of 2-Arachidonoylglycerol Edit

Chemical Property:

Appearance/Colour:Liquid
Vapor Pressure:1.78E-12mmHg at 25°C
Refractive Index:1.507
Boiling Point:508.6 °C at 760 mmHg
PKA:13.54±0.10(Predicted)
Flash Point:163 °C
PSA：66.76000
Density:0.992 g/cm³
LogP:5.02850
Storage Temp.:−20°C
XLogP3:5.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:18
Exact Mass:378.27700969
Heavy Atom Count:27
Complexity:445

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Arachidonyl glycerol ^*data from reagent suppliers

Safty Information:

Pictogram(s): F,Xn
Hazard Codes:F,Xn
Statements: 11-20/21/22-36
Safety Statements: 26-36/37-16

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCC=CCC=CCC=CCC=CCCCC(=O)OC(CO)CO
Isomeric SMILES:CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OC(CO)CO
Uses 2-Arachidonoylglycerol is a major endocannabinoid, which can inhibit synaptic transmission by presynaptic cannabinoid CB1 receptors. It plays an inhibitory role in the bombesin-induced activation of central adrenomedullary outflow in rats.

Technology Process of 2-Arachidonoylglycerol

There total 14 articles about 2-Arachidonoylglycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 439146-25-5
2-O-arachidonoyl-1,3-bis-O-(trifluoroacetyl)glycerol

: 53847-30-6
2-arachidonoyl glycerol

Guidance literature:: With pyridine; methanol; In dichloromethane; pentane; for 3h; from -20 degC to rt;
DOI:10.1016/S0040-4039(02)00116-8

Reference yield: 86.0%

: 2-arachidonylglycerol 1,3-phenylboronate ester

: 53847-30-6
2-arachidonoyl glycerol

Guidance literature:: With water; In methanol;
DOI:10.1016/S0040-4039(00)00469-X

Reference yield: 75.0%

: 1274596-36-9
2-((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyloxy)propane-1,3-diyl dibutyrate

: 53847-30-6
2-arachidonoyl glycerol

Guidance literature:: With Rhizomucor miehei lipase; ethanol; at 20 ℃; for 24h; regiospecific reaction; Enzymatic reaction;
DOI:10.1016/j.tet.2012.04.101