3-Aminopropanimidamide--hydrogen bromide (1/1)

Base Information

• Chemical Name: 3-Aminopropanimidamide--hydrogen bromide (1/1)
• CAS No.: 77152-88-6
• Molecular Formula: C3H9N3
• Molecular Weight: 248.948
• DSSTox Substance ID: DTXSID10507813
• NSC Number: 108873
• Mol file: 77152-88-6.mol

Synonyms:77152-88-6;3-Aminopropanimidamide--hydrogen bromide (1/1);SCHEMBL9510430;DTXSID10507813;NSC108873;NSC-108873

Chemical Property of 3-Aminopropanimidamide--hydrogen bromide (1/1)

Chemical Property:

• Vapor Pressure: 0.809mmHg at 25°C
• Boiling Point: 182.5°C at 760 mmHg
• Flash Point: 64.2°C
• Density: 1.23g/cm³
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 167.00581
• Heavy Atom Count: 7
• Complexity: 50

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(CN)C(=N)N.Br

Technology Process of 3-Aminopropanimidamide--hydrogen bromide (1/1)

There total 1 articles about 3-Aminopropanimidamide--hydrogen bromide (1/1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

3-(p-toluenesulfonylamino)-propionamidine (91977-72-9) → (1-amino-3-ammoniopropylidene)ammonium dihydrobromide (77152-88-6)

Guidance literature:

With hydrogen bromide; phenol; In acetic acid; for 2h; Heating;

DOI:10.1039/b404962d

Reference yield: 93.5%

(1-amino-3-ammoniopropylidene)ammonium dihydrobromide (77152-88-6) + N-succinimidyl-<1-methyl-3-<1-methyl-3-<1-methyl-3-<4-bis(2-chloroethyl)aminophenylamido>-pyrazole-5-carboxamido>pyrazole-5-carboxamido>>pyrazole-5-carboxylate (223437-73-8) → C29H35Cl2N13O4*ClH

Guidance literature:

With sodium hydrogencarbonate; In 1,4-dioxane; water; N,N-dimethyl-formamide; for 18h; Ambient temperature;

DOI:10.1016/S0968-0896(98)00205-3

Reference yield: 50.0%

(1-amino-3-ammoniopropylidene)ammonium dihydrobromide (77152-88-6) + 4-({4-[(4-Formylamino-1-propyl-1H-pyrrole-2-carbonyl)-amino]-1H-pyrrole-2-carbonyl}-amino)-1-methyl-1H-pyrrole-2-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester → C23H29N9O4*BrH (107164-67-0)

Guidance literature:

With sodium hydrogencarbonate; In 1,4-dioxane; water;

upstream raw materials:

3-(p-toluenesulfonylamino)-propionamidine

Downstream raw materials:

distamycin A hydrochloride

C₂₁H₂₅N₉O₄

C₂₁H₂₅N₉O₄

C₂₃H₂₉N₉O₄

Refernces

• 1、 Bailly, Christian,Houssin, Raymond,Bernier, Jean-Luc,Henichart, Jean-Pierre. "DEPSIPEPTIDE ANALOGS OF THE ANTITUMOR DROG DISTAMYCIN CONTAINING THIAZOLE AMINO ACIDS RESIDUES". . p. 5833 - 5844. Retrieved 2007/10/02.