4(1H)-Pteridinone,2-amino-7,8-dihydro-6-methyl-(9CI)

Base Information

• Chemical Name: 4(1H)-Pteridinone,2-amino-7,8-dihydro-6-methyl-(9CI)
• CAS No.: 17377-13-8
• Molecular Formula: C7H9 N5 O
• Molecular Weight: 179.181
• Hs Code.: 2933990090
• Mol file: 17377-13-8.mol

Synonyms:4(1H)-Pteridinone,2-amino-7,8-dihydro-6-methyl- (9CI); 4-Pteridinol,2-amino-7,8-dihydro-6-methyl- (6CI,7CI); 2-Amino-4-hydroxy-6-methyl-7,8-dihydropteridine;6-Methyl-7,8-dihydropterin; 7,8-Dihydro-6-methylpterin; NSC 212476

Chemical Property of 4(1H)-Pteridinone,2-amino-7,8-dihydro-6-methyl-(9CI)

Chemical Property:

• Vapor Pressure: 0.000256mmHg at 25°C
• Boiling Point: 323.8°Cat760mmHg
• Flash Point: 149.6°C
• PSA: 96.16000
• Density: 1.78g/cm³
• LogP: 0.02480

Purity/Quality:

99% ^*data from raw suppliers

2-amino-7,8-dihydro-6-methyl-4(3H)-Pteridinone 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4(1H)-Pteridinone,2-amino-7,8-dihydro-6-methyl-(9CI)

There total 16 articles about 4(1H)-Pteridinone,2-amino-7,8-dihydro-6-methyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-methyldihydropterin hydrochloride (102069-94-3) → 2-amino-6-methylpteridin-4(1H)-one (708-75-8) + 6-Methyl-7,8-dihydropterin (17377-13-8) + (6-R,S)-6-methyl-5,6,7,8-tetrahydropterin dihydrochloride (35695-16-0,66216-72-6,67129-01-5,67129-04-8,69113-63-9,74879-09-7,74923-39-0,82970-20-5)

Guidance literature:

With hydrogenchloride; Yields of byproduct given; pH 3.0;

DOI:10.1016/S0040-4039(00)98709-4

Reference yield:

6-methyl-5,6,7,8-tetrahydrobopterin (942-41-6) + ortoquinone (583-63-1) → 6-Methyl-7,8-dihydropterin (17377-13-8) + benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9)

Guidance literature:

With tyrosinase; Enzymatic reaction;

DOI:10.1271/bbb.90924

Reference yield:

6-aminomethyl-7,8-dihydro-6H-pterin (120483-45-6) → 6-Methyl-7,8-dihydropterin (17377-13-8) + 7,8-dihydropterin (17838-80-1)

Guidance literature:

With Tris buffer; Rate constant; pH 7.5;

DOI:10.1071/CH9880667

upstream raw materials:

2-amino-6-methylpteridin-4(1H)-one

6-methyl-5,6,7,8-tetrahydrobopterin

6-methyldihydropterin hydrochloride

6-aminomethyl-7,8-dihydro-6H-pterin

Downstream raw materials:

2-amino-6-methylpteridin-4(1H)-one

(S)-6-methyl-5,6,7,8-tetrahydropterin

2,5-dihydroxybenzoic acid.

Refernces

• 1、 Viscontini,Cogoli-Greuter. "-". . p. 1125,1128. Retrieved 1971.
• 2、 Lunte,Kissinger. "INVESTIGATION OF 6-METHYLPTERIN ELECTROCHEMISTRY BY DUAL-ELECTRODE LIQUID CHROMATOGRAPHY/ELECTROCHEMISTRY.". . p. 658 - 663. Retrieved 1984.
• 3、 Garcia-Molina, Francis,Munoz-Munoz, Joseph Louis,Martinez-Ortiz, Francis,Tudela, Joseph,Garcia-Canovas, Francis,Rodriguez-Lopez, Joseph Neptune. "Effects of tetrahydropterines on the generation of quinones catalyzed by tyrosinase". scheme or table. p. 1108 - 1109. Retrieved 2011/05/04.
• 4、 Matsuura, Sadao,Sugimoto, Takashi,Murata, Shizuaki. "SYNTHESIS OF QUINONOID 6-METHYL AND 6,7-DIMETHYLDIHYDROPTERINS". . p. 4003 - 4004. Retrieved 2007/10/02.