Phosphine oxide, dioctyl-

Base Information

• Chemical Name: Phosphine oxide, dioctyl-
• CAS No.: 3011-82-3
• Molecular Formula: C16H35 O P
• Molecular Weight: 274.427
• Hs Code.: 2931900090
• DSSTox Substance ID: DTXSID70952522
• Mol file: 3011-82-3.mol

Synonyms:di-n-octylphosphine oxide

Chemical Property of Phosphine oxide, dioctyl-

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 51.21000
• Density: g/cm³
• LogP: 6.53480
• XLogP3: 5.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 14
• Exact Mass: 273.234727701
• Heavy Atom Count: 18
• Complexity: 162

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCC[P+](=O)CCCCCCCC

Technology Process of Phosphine oxide, dioctyl-

There total 2 articles about Phosphine oxide, dioctyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

1-bromo-octane (111-83-1) → oxyde de dioctyl phosphine (3011-82-3) + cyanex-921 (78-50-2) + octylphosphinic acid (6196-68-5)

Guidance literature:

With potassium hydroxide semihydrate; phosphorus; N-benzyl-N,N,N-triethylammonium chloride; In toluene; at 60 - 62 ℃; for 5h; Reagent/catalyst; Inert atmosphere;

DOI:10.1016/j.mencom.2019.05.030

Reference yield:

1-bromo-octane (111-83-1) → oxyde de dioctyl phosphine (3011-82-3) + cyanex-921 (78-50-2)

Guidance literature:

With phosphorus; potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In tetrahydrofuran; at 60 - 65 ℃; for 6h; Yield given;

Reference yield: 100.0%

oxyde de dioctyl phosphine (3011-82-3) + benzyl chloride (100-44-7) → benzyl dioctyl phosphine oxide (35794-29-7)

Guidance literature:

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In toluene; at 65 ℃; for 3h; Product distribution; preparation of unsymmetrical tertiary phosphine oxides with chloromethylated compounds; half lives with different phase transfer catalysts;

upstream raw materials:

1-bromo-octane

Downstream raw materials:

dioctylphosphinic acid

1-Dioctylphosphinoyl-cyclohexanol

2-chloro-α-dioctylphosphinoyl-benzyl alcohol

α-dioctylphosphinoyl-benzyl alcohol

Refernces

• 1、 Trofimov, B. A.,Gusarova, N. K.,Malysheva, S. F.,Rakhmatulina, T. N.,Voronkov, M. G.,et al.. "SUPERBASE-INDUCED GENERATION OF PHOSPHIDE AND PHOSPHINITE IONS AS APPLIED IN ORGANIC SYNTHESIS". . p. 271 - 274. Retrieved 2007/10/02.