5H-Indeno[1,2-c]pyridine

Base Information

• Chemical Name: 5H-Indeno[1,2-c]pyridine
• CAS No.: 244-42-8
• Molecular Formula: C₁₂H₉N
• Molecular Weight: 167.21
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID30497085
• Nikkaji Number: J79.537B
• Wikidata: Q82346442
• Mol file: 244-42-8.mol

Synonyms:5H-Indeno[1,2-c]pyridine;3-azafluorene;244-42-8;SCHEMBL3075871;DTXSID30497085;QXVYBAAJUSTEBJ-UHFFFAOYSA-N

Chemical Property of 5H-Indeno[1,2-c]pyridine

Chemical Property:

• PSA: 12.89000
• LogP: 2.65280
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 167.073499291
• Heavy Atom Count: 13
• Complexity: 190

Purity/Quality:

99% ^*data from raw suppliers

5H-INDENO[1,2-C]PYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C2=C(C=NC=C2)C3=CC=CC=C31

Technology Process of 5H-Indeno[1,2-c]pyridine

There total 4 articles about 5H-Indeno[1,2-c]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 9.0%

methyl-4 phenyl-3 pyridine (19352-29-5) → 3-azafluorene (244-42-8)

Guidance literature:

K-16; In benzene; at 520 - 540 ℃; for 5h;

DOI:10.1007/BF00504113

Reference yield:

2-phenylethanol (60-12-8) → 3-azafluorene (244-42-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 15 percent / NH₃ / Cd-Ca phosphate

2: 9 percent / K-16 / benzene / 5 h / 520 - 540 °C

With ammonia; Cd-Ca phosphate; In benzene;

DOI:10.1007/BF00504113

Reference yield:

phenylacetaldehyde (122-78-1) → 3-azafluorene (244-42-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 27 percent / NH₃ / Cd-Ca phosphate / 375 - 400 °C

2: 9 percent / K-16 / benzene / 5 h / 520 - 540 °C

With ammonia; Cd-Ca phosphate; In benzene;

DOI:10.1007/BF00504113

upstream raw materials:

methyl-4 phenyl-3 pyridine

2-phenylethanol

phenylacetaldehyde

Downstream raw materials:

5H-indeno[1,2-c]pyridin-5-one

Refernces