D-Fructose

Base Information

• Chemical Name: D-Fructose
• CAS No.: 7660-25-5
• Molecular Formula: C6H12O6
• Molecular Weight: 180.158
• Hs Code.: 1702600000
• Nikkaji Number: J1.167.127F
• Wikipedia: Fructose
• Wikidata: Q27117234
• Metabolomics Workbench ID: 55668
• ChEMBL ID: CHEMBL2325229
• Mol file: 7660-25-5.mol

Synonyms:Apir Levulosa;Fleboplast Levulosa;Fructose;Levulosa;Levulosa Baxter;Levulosa Braun;Levulosa Grifols;Levulosa Ibys;Levulosa Ife;Levulosa Mein;Levulosa, Apir;Levulosa, Fleboplast;Levulosado Bieffe Medit;Levulosado Braun;Levulosado Vitulia;Levulose;Plast Apyr Levulosa Mein

Chemical Property of D-Fructose

Chemical Property:

• Appearance/Colour: White Crystalline powder
• Vapor Pressure: 1.36E-09mmHg at 25°C
• Melting Point: 100 - 110oC
• Refractive Index: 1.616
• Boiling Point: 401.1 °C at 760 mmHg
• PKA: 11.52±0.70(Predicted)
• Flash Point: 196.4 °C
• PSA: 110.38000
• Density: 1.758 g/cm³
• LogP: -3.21980
• Water Solubility.: 3750 g/L (20℃)
• XLogP3: -2.8
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 180.06338810
• Heavy Atom Count: 12
• Complexity: 162

Purity/Quality:

99%, ^*data from raw suppliers

Fructose 98% ^*data from reagent suppliers

Safty Information:

• Safety Statements: S24/25:

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(C(C(C(O1)(CO)O)O)O)O
• Isomeric SMILES: C1[C@H]([C@H]([C@@H](C(O1)(CO)O)O)O)O
• Recent ClinicalTrials: BaRiatric Surgery AnD FRUctose Handeling In Obese subjecTs
• Recent NIPH Clinical Trials: Comparisons of different carbohydrate ingestions on exercise performance and thermoregulation

Technology Process of D-Fructose

There total 7 articles about D-Fructose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.6%

thymidine-5′-diphosphate trisodium salt + Sucrose (57-50-1) → D-fructose (7660-25-5) + thymidine 5'-phosphate (365-07-1,15108-71-1,60363-32-8,96744-88-6,132696-16-3,143838-77-1) + thymidine 5'-(α-D-glucopyranosyl diphosphate) (2196-62-5)

Guidance literature:

With NaOH buffer; bovine serum albumin; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid; at 30 ℃; for 6.66667h; sucrose synthase;

Reference yield:

Sucrose (57-50-1) → β-D-glucose (492-61-5) + alpha-D-glucopyranose (492-62-6) + D-fructose (7660-25-5) + α-D-fructofuranose (10489-79-9) + D-fructose (470-23-5)

Guidance literature:

With sodium acetate buffer pH 5.0; In water-d2; at 20 ℃; for 1h; Product distribution; baker's yeast invertase or candida utilis invertase;

Reference yield:

Sucrose (57-50-1) → β-D-glucose (492-61-5) + alpha-D-glucopyranose (492-62-6) + D-fructose (7660-25-5) + D-fructose (470-23-5)

Guidance literature:

With invertase from Saccheromyces cerevisea; at 24.84 ℃; pH=5; Concentration; Reagent/catalyst; Kinetics; aq. acetate buffer; Enzymatic reaction;

DOI:10.1016/j.bbapap.2011.10.011

upstream raw materials:

Sucrose

α-D-lactulose

D-Glucose

Downstream raw materials:

β-D-fructopyranose-2,3:4,5-bis(phenylboronate)

D-Fructose

mannitol

D-sorbitol

Refernces

• 1、 Exnowitz, Franziska,Meyer, Bernd,Hackl, Thomas. "NMR for direct determination of Km and Vmax of enzyme reactions based on the Lambert W function-analysis of progress curves". experimental part. p. 443 - 449. Retrieved 2012/07/13.
• 2、 Heinen, Annemieke W.,Peters, Joop A.,Van Bekkum, Herman. "The combined hydrolysis and hydrogenation of inulin catalyzed by bifunctional Ru/C". . p. 381 - 390. Retrieved 2007/10/03.