4,4'-Iminodiphenol

Base Information

• Chemical Name: 4,4'-Iminodiphenol
• CAS No.: 1752-24-5
• Molecular Formula: C12H11 N O2
• Molecular Weight: 201.225
• Hs Code.: 2922299090
• European Community (EC) Number: 217-136-3
• UNII: GT5H6Q4HYA
• DSSTox Substance ID: DTXSID6061945
• Nikkaji Number: J7.767D
• Wikidata: Q81989759
• ChEMBL ID: CHEMBL470673
• Mol file: 1752-24-5.mol

Synonyms:4,4'-Iminodiphenol;1752-24-5;Phenol, 4,4'-iminobis-;4,4'-azanediyldiphenol;4-(4-hydroxyanilino)phenol;Leucoindophenol;Bis(p-hydroxyphenyl)amine;4,4'-Dihydroxydiphenylamine;4,4'-Iminobisphenol;Bis(4-hydroxyphenyl)amine;Phenol, 4,4'-iminodi-;EINECS 217-136-3;GT5H6Q4HYA;BRN 2104633;4-13-00-01064 (Beilstein Handbook Reference);Dioxydiphenylamin;UNII-GT5H6Q4HYA;CBDivE_002778;PARACETAMOL IMPURITY M;4,4-AZANEDIYLDIPHENOL;SCHEMBL306231;CHEMBL470673;DTXSID6061945;STL282748;AKOS003632031;SB34282;BS-50096;HY-135324;LS-104732;CS-0111408;PARACETAMOL IMPURITY M [EP IMPURITY]

Chemical Property of 4,4'-Iminodiphenol

Chemical Property:

• Melting Point: 169 °C
• Refractive Index: 1.5560 (estimate)
• Boiling Point: 363°Cat760mmHg
• PKA: 10.55±0.26(Predicted)
• Flash Point: 158.8°C
• PSA: 52.49000
• Density: 1.32g/cm³
• LogP: 2.91440
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 201.078978594
• Heavy Atom Count: 15
• Complexity: 162

Purity/Quality:

99%, ^*data from raw suppliers

4,4''-Iminodiphenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1NC2=CC=C(C=C2)O)O
• Uses: 4,4''-Iminodiphenol is derived from 4,4''-Dimethoxydiphenylamine (D461065), which is a diphenylamine derivative used as a chemical additive for cured rubber. 4,4''-Dimethoxydiphenylamine is highly toxic and may potentially induce chromosome abberation.

Technology Process of 4,4'-Iminodiphenol

There total 22 articles about 4,4'-Iminodiphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

bis(4-methoxyphenyl)amine (101-70-2) → 4,4'-dihydroxydiphenylamine (1752-24-5)

Guidance literature:

With boron tribromide; In dichloromethane; at -80 ℃; for 24h; Inert atmosphere;

DOI:10.1039/c7cc08510a

Reference yield:

4-amino-phenol (123-30-8) → 4,4'-dihydroxydiphenylamine (1752-24-5)

Guidance literature:

With iodine; at 200 ℃;

Reference yield:

4-amino-phenol (123-30-8) + hydroquinone (123-31-9,8027-02-9) → 4,4'-dihydroxydiphenylamine (1752-24-5)

Guidance literature:

With calcium chloride; at 160 - 180 ℃;

upstream raw materials:

indophenol

p-aminophenol hydrochloride

4-amino-phenol

hydroquinone

Downstream raw materials:

4,4'-di-n-butoxydiphenylamine

N,N-bis-(4-acetoxy-phenyl)-acetamide

thionol

indophenol

Refernces

• 1、 Chang, Guanjun,Wang, Cheng,Du, Mengqi,Liu, Shenye,Yang, Li. "Metal-coordination crosslinked: N -polyindoles as recyclable high-performance thermosets and nondestructive detection for their tensile strength and glass transition temperature". supporting information. p. 2906 - 2909. Retrieved 2018/03/23.
• 2、 Bonastre, J.,Castetbon, A.,Andrieu, X.. "MECANISMES DE REDUCTION ELECTROCHIMIQUE DES QUINONES MONO ET DICHLORIMINE SUR PLATINE. ETUDE ET STRUCTURE DES COMPOSES OBTENUS LORS DE COULOMETRIES A FORTE CONCENTRATION". . p. 145 - 152. Retrieved 2007/10/02.