5,5'-Diselenodivaleric acid

Base Information

• Chemical Name: 5,5'-Diselenodivaleric acid
• CAS No.: 18285-95-5
• Molecular Formula: C10H18O4Se2
• Molecular Weight: 0
• Hs Code.: 2917190090
• Mol file: 18285-95-5.mol

Synonyms:5-[(5-hydroxy-5-oxopentyl)diselanyl]pentanoic acid;5,5'-Diseleno-divaleriansaeure;Diselenodi-n-valeric acid;Valeric acid,5,5'-diselenodi;Pentanoic acid,5,5'-diselenobis;6,7-Diselena-dodecandisaeure;5,5'-Diseleno-di-n-valeriansaeure;Bis-(4-carboxy-butyl)-diselenid;Pentanoic acid,5'-diselenobis;6,7-diselena-dodecanedioic acid;Valeric acid,5'-diselenodi;

Chemical Property of 5,5'-Diselenodivaleric acid

Chemical Property:

• Boiling Point: 521.7oC at 760 mmHg
• Flash Point: 269.3oC
• PSA: 74.60000
• LogP: 1.65620

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5,5'-Diselenodivaleric acid

There total 2 articles about 5,5'-Diselenodivaleric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

5-bromopentanoic acid (2067-33-6) → 5,5'-Diseleno-divaleriansaeure (18285-95-5)

Guidance literature:

With selenium; sodium tetrahydroborate; In tetrahydrofuran; water; at 50 ℃; Inert atmosphere;

DOI:10.1002/anie.201810588

Reference yield:

→ 5,5'-Diseleno-divaleriansaeure (18285-95-5)

Guidance literature:

nach Fregda;

Reference yield:

5,5'-Diseleno-divaleriansaeure (18285-95-5) + (4-nitrophenyl)ethyl bromide (5339-26-4) → 5-(4-Nitrophenylethylseleno)valeriansaeure (34835-22-8)

Guidance literature:

Multistep reaction; (i) HOCH2SO2H , aq. NH3, (ii) /BRN= 1909321/;

upstream raw materials:

5-bromopentanoic acid

Downstream raw materials:

5-(4-Nitrophenylethylseleno)valeriansaeure

5-(β-Phenylethylseleno)-valeriansaeure

5-(benzylseleno)pentanoic acid

5'-(4-Methylbenzylseleno)-valeriansaeure

Refernces

• 1、 Cao, Wei,Gao, Shiqian,Li, Tianyu,Pan, Shuojiong,Sun, Chenxing,Xiang, Wentian,Xu, Huaping. "Diselenide–Pemetrexed Assemblies for Combined Cancer Immuno-, Radio-, and Chemotherapies". . p. 2700 - 2704. Retrieved 2020.