SALOR-INT L497096-1EA

Base Information

• Chemical Name: SALOR-INT L497096-1EA
• CAS No.: 6339-04-4
• Molecular Formula: C10H11NO4
• Molecular Weight: 209.202
• Hs Code.: 2924299090
• Mol file: 6339-04-4.mol

Synonyms:2-(3-acetamidophenoxy)acetic acid;

Chemical Property of SALOR-INT L497096-1EA

Chemical Property:

• Vapor Pressure: 2.4E-09mmHg at 25°C
• Boiling Point: 462.3°C at 760 mmHg
• PKA: 3.13±0.10(Predicted)
• Flash Point: 233.4°C
• PSA: 75.63000
• Density: 1.326g/cm³
• LogP: 1.18140
• Storage Temp.: 2-8°C

Purity/Quality:

99%min ^*data from raw suppliers

3-AcetamidophenoxyaceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of SALOR-INT L497096-1EA

There total 4 articles about SALOR-INT L497096-1EA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl bromoacetate (105-36-2) + meta-hydroxyacetanilide (621-42-1) → 2-(3-acetamidophenoxy)acetic acid (6339-04-4)

Guidance literature:

ethyl bromoacetate; meta-hydroxyacetanilide; With potassium carbonate; In acetonitrile; at 80 ℃; for 4h;

With water; sodium hydroxide; In ethanol; at 50 ℃; for 4h;

Reference yield:

chloroacetic acid (79-11-8) + meta-hydroxyacetanilide (621-42-1) → 2-(3-acetamidophenoxy)acetic acid (6339-04-4)

Guidance literature:

With sodium hydroxide;

Reference yield:

furan-2,3,5(4H)-trione pyridine (1:1) + chloroacetic acid (79-11-8) + meta-hydroxyacetanilide (621-42-1) → 2-(3-acetamidophenoxy)acetic acid (6339-04-4)

Guidance literature:

upstream raw materials:

chloroacetic acid

meta-hydroxyacetanilide

ethyl bromoacetate

Downstream raw materials:

2-(3-acetamidophenoxy)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)acetamide

(2,4,6-Trijod-3-hydroxy-phenoxy)-essigsaeure

3-hydroxyphenoxyacetic acid

(3-amino-phenoxy)-acetic acid

Refernces

• 1、 -. "PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF". Paragraph 00296. . Retrieved 2014/07/08.