guanosine diphosphate 2-deoxy-2-fluoromannose ester

Base Information

• Chemical Name: guanosine diphosphate 2-deoxy-2-fluoromannose ester
• CAS No.: 67341-46-2
• Molecular Formula: C16H24FN5O15P2
• Molecular Weight: 607.337
• Mol file: 67341-46-2.mol

Synonyms:

Chemical Property of guanosine diphosphate 2-deoxy-2-fluoromannose ester

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 1037.9°C at 760 mmHg
• Flash Point: 581.5°C
• PSA: 331.11000
• Density: 2.46g/cm³
• LogP: -3.07010

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of guanosine diphosphate 2-deoxy-2-fluoromannose ester

There total 1 articles about guanosine diphosphate 2-deoxy-2-fluoromannose ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-deoxy-2-fluoro-D-mannopyranoside (7226-39-3,7241-17-0,28876-44-0,38711-37-4,55449-80-4,62182-10-9,62182-14-3,86783-82-6,98856-44-1,98856-45-2,98856-46-3,31077-88-0) + Guanosine 5'-triphosphate (86-01-1,72490-81-4) → guanosine-5’-diphospho-2′′-fluoro-α-D-mannopyranosyl (67341-46-2) + guanosine-5'-diphosphate (146-91-8)

Guidance literature:

With guanosine 50-diphosphate (GDP)-mannose pyrophosphorylasefrom Pyrococcus furiosus; N-acetylhexosamine 1-kinase from Bifidobacterium infantis; magnesium chloride; Escherichia coli inorganic pyrophosphatase; In aq. buffer; at 37 ℃; for 24h; pH=8; Enzymatic reaction;

DOI:10.1021/ol402585c

upstream raw materials:

2-deoxy-2-fluoro-D-mannopyranoside

Guanosine 5'-triphosphate

Refernces