2,4,6-TRIBROMOIODOBENZENE

Base Information

• Chemical Name: 2,4,6-TRIBROMOIODOBENZENE
• CAS No.: 21521-51-7
• Molecular Formula: C6H2Br3I
• Molecular Weight: 440.698
• Hs Code.: 2903999090
• Mol file: 21521-51-7.mol

Synonyms:1,3,5-Tribromo-2-iodobenzene;1,3,5-Tribromo-4-iodobenzene;1-Iodo-2,4,6-tribromobenzene;NSC 159038;

Chemical Property of 2,4,6-TRIBROMOIODOBENZENE

Chemical Property:

• Vapor Pressure: 0.000131mmHg at 25°C
• Melting Point: 103-104℃
• Refractive Index: 1.705
• Boiling Point: 344.475 °C at 760 mmHg
• Flash Point: 162.133 °C
• PSA: 0.00000
• Density: 2.753 g/cm³
• LogP: 4.57870
• Storage Temp.: 2-8°C
• Solubility.: Hexane

Purity/Quality:

99%, ^*data from raw suppliers

2,4,6-Tribromoiodobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,4,6-Tribromoiodobenzene is an tetra substituted benzene derivative and an intermediate in the synthesis of brominated fire retardants.

Technology Process of 2,4,6-TRIBROMOIODOBENZENE

There total 11 articles about 2,4,6-TRIBROMOIODOBENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,4,6-tribromobenzenediazonium 4-methylbenzenesulfonate (1059625-69-2) → 2,4,6-tribromoiodobenzene (21521-51-7)

Guidance literature:

With potassium iodide; In water; at 20 ℃; for 0.166667h;

DOI:10.1021/ol8013528

Reference yield: 84.0%

C10H12Br3N3 (401631-91-2) → 1,3,5-trisbromobenzene (626-39-1) + 2,4,6-tribromoiodobenzene (21521-51-7)

Guidance literature:

With tetrafluoroboric acid; hydrogen iodide; In acetonitrile; at 60 ℃; for 24h;

DOI:10.1055/s-2001-18072

Reference yield: 83.0%

2,4,6-tribromoaniline (147-82-0) → 2,4,6-tribromoiodobenzene (21521-51-7)

Guidance literature:

2,4,6-tribromoaniline; With nitrosyl acetate; acetic acid; at -5 - 0 ℃; for 2h;

With potassium iodide; for 16h; Reagent/catalyst; Temperature;

upstream raw materials:

diazotiertes 2.4.6-Tribrom-anilin

2,4,6-tribromoaniline

C₁₀H₁₂Br₃N₃

2,4,6-tribromobenzenediazonium 4-methylbenzenesulfonate

Downstream raw materials:

1-bromo-3,5-diphenylbenzene

2,2',4,4',6,6'-hexabromo-1,1'-biphenyl

2,4,6-tribromostyrene

2,4,6-tribromo-1,3-dinitrobenzene

Refernces

• 1、 Warsitz, Michael,Doye, Sven. "Linear Hydroaminoalkylation Products from Alkyl-Substituted Alkenes". supporting information. p. 15121 - 15125. Retrieved 2020/10/23.
• 2、 Cornaggia, Claudio,Gundala, Sivaji,Manoni, Francesco,Gopalasetty, Nagaraju,Connon, Stephen J.. "Catalytic formal cycloadditions between anhydrides and ketones: Excellent enantio and diastereocontrol, controllable decarboxylation and the formation of adjacent quaternary stereocentres". supporting information. p. 3040 - 3046. Retrieved 2016/03/19.