Cyclobutylmethylamine hydrochloride

Base Information

• Chemical Name: Cyclobutylmethylamine hydrochloride
• CAS No.: 5454-82-0
• Molecular Formula: C5H11N
• Molecular Weight: 121.61
• Hs Code.: 2921300090
• Mol file: 5454-82-0.mol

Synonyms:Cyclobutylmethylamine hydrochloride;CyclobutaneMethanaMine hydrochloride;CyclobutaneMethanaMine, hydrochloride (1:1);(AMinoMethyl)cyclobutane hydrochloride;1-CyclobutylMethylaMine hydrochloride;CyclobutaneMethanaMine HCl;CyclobutylMethylaMine, HCl;(aMinoMethyl)cyclobutane hcl

Chemical Property of Cyclobutylmethylamine hydrochloride

Chemical Property:

• Boiling Point: 90.6 °C at 760 mmHg
• Flash Point: 2.1 °C
• PSA: 26.02000
• Density: 0.889 g/cm³
• LogP: 2.24750
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility.: DMSO (Slightly), Methanol (Slightly), Water (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

CyclobutylmethylamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclobutylmethylamine hydrochloride

There total 2 articles about Cyclobutylmethylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

cyclobutanecarbonitrile (4426-11-3) → cyclobutylmethylamine hydrochloride (5454-82-0)

Guidance literature:

cyclobutanecarbonitrile; With diborane; In tetrahydrofuran; Inert atmosphere; Reflux;

With hydrogenchloride; In methanol; at 20 ℃; for 2.5h; Reflux;

Reference yield:

→ cyclobutylmethylamine hydrochloride (5454-82-0)

Guidance literature:

Reference yield: 94.0%

2-fluoro-4-hydroxybenzaldehyde (348-27-6) + cyclobutylmethylamine hydrochloride (5454-82-0) → 4-(((cyclobutylmethyl)amino)methyl)-3-fluorophenol (1582778-48-0)

Guidance literature:

2-fluoro-4-hydroxybenzaldehyde; cyclobutylmethylamine hydrochloride; With sodium carbonate; magnesium sulfate; In dichloromethane; at 20 ℃;

With sodium tetrahydroborate; In dichloromethane; for 16h;

upstream raw materials:

cyclobutanecarbonitrile

Downstream raw materials:

methylidenecyclobutane

Cyclopentanol

cyclobutanemethanol

cyclopentene

Refernces

• 1、 -. "NOVEL COMPOUNDS". Page/Page column 19. . Retrieved 2015/03/04.
• 2、 -. "PYRIDINE DERIVATIVES AS CONNABINOID RECEPTOR MODULATORS". Page/Page column 22. . Retrieved 2008/06/13.