N-Vinylpyrrolidine

Base Information

• Chemical Name: N-Vinylpyrrolidine
• CAS No.: 4540-16-3
• Molecular Formula: C6H11N
• Molecular Weight: 97.16
• Hs Code.: 2933990090
• UNII: BGQ0JZ9FNA
• DSSTox Substance ID: DTXSID70196500
• Nikkaji Number: J1.326.047H
• Wikidata: Q27274658
• Mol file: 4540-16-3.mol

Synonyms:N-Vinylpyrrolidine;1-vinylpyrrolidine;4540-16-3;1-ethenylpyrrolidine;1-ETHENYL-PYRROLIDINE;Pyrrolidine, 1-ethenyl-;BGQ0JZ9FNA;UNII-BGQ0JZ9FNA;pyrrolidinoethylene;vinyl pyrrolidine;N-vinyl-2-pyrrolidine;N-VINYLPYROLIDONE-;PYRROLIDINE, 1-VINYL-;DTXSID70196500;UDJZTGMLYITLIQ-UHFFFAOYSA-N;AM85776;A902105;Q27274658

Chemical Property of N-Vinylpyrrolidine

Chemical Property:

• Vapor Pressure: 9.64mmHg at 25°C
• Boiling Point: 130.6°C at 760 mmHg
• PKA: 8.49±0.20(Predicted)
• Flash Point: 24.5°C
• PSA: 3.24000
• Density: 0.965g/cm³
• LogP: 1.16360
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 97.089149355
• Heavy Atom Count: 7
• Complexity: 62.6

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CN1CCCC1

Technology Process of N-Vinylpyrrolidine

There total 1 articles about N-Vinylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyrrolidine (123-75-1) + acetaldehyde (75-07-0,9002-91-9) → pyrrolidinoethylene (4540-16-3)

Guidance literature:

With potassium carbonate; In toluene; at 20 ℃; for 12h;

DOI:10.1055/s-2002-25363

Reference yield: 77.0%

C16H10ClF2N (1240409-71-5) + pyrrolidinoethylene (4540-16-3) → 1-(3,3-difluoro-9-phenyl-2,3-dihydro-1H-cyclopenta[b]quinolin-1-yl)pyrrolidin-2S21-one

Guidance literature:

With tris(2,2'-bipyridyl)ruthenium dichloride; tributyl-amine; potassium carbonate; In acetonitrile; at 20 ℃; for 10h; Inert atmosphere; Irradiation;

DOI:10.1021/acs.orglett.6b00119

Reference yield: 67.0%

3-(6-chloro-4-oxo-4H-chromen-3-yl)prop-2-enoic acid (55593-65-2) + pyrrolidinoethylene (4540-16-3) → 3-(5-chloro-2-hydroxybenzoyl)benzoic acid

Guidance literature:

3-(6-chloro-4-oxo-4H-chromen-3-yl)prop-2-enoic acid; pyrrolidinoethylene; In dichloromethane; at 20 ℃; for 1h;

With hydrogenchloride; In dichloromethane; water; at 20 ℃; for 0.5h;

DOI:10.1134/S1070363219120223

upstream raw materials:

pyrrolidine

acetaldehyde

Downstream raw materials:

4,6,8-trimethylazulene

ethyl 5,6-diphenylpyridine-2-carboxylate

Refernces

• 1、 Nagel, Matthias,Hansen, Hans-Jürgen. "From phenols to azulenes: An extended and versatile route to polyalkylated azulenes with variable substitution patterns at the seven- and five-membered ring". . p. 692 - 696. Retrieved 2007/10/03.