TSCHIMGINE

Base Information

• Chemical Name: TSCHIMGINE
• CAS No.: 38970-50-2
• Molecular Formula: C17H22O3
• Molecular Weight: 274.36
• Hs Code.: 2918290000
• Mol file: 38970-50-2.mol

Synonyms:L-TRP-GLY;TRP-GLY CRYSTALLINE;tryptophylglycine;L-tryptophyl-Glycine;l-tschimgin;N-L-Tryptophylglycine;TRP-GLY;Trp-Gly-OH;tryptylglycine;L-Trp-Gly-OH;

Chemical Property of TSCHIMGINE

Chemical Property:

• Vapor Pressure: 2.29E-06mmHg at 25°C
• Boiling Point: 381.6°C at 760 mmHg
• Flash Point: 153.2°C
• PSA: 46.53000
• Density: 1.16g/cm³
• LogP: 3.37370

Purity/Quality:

99%, ^*data from raw suppliers

TSCHIMGINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of TSCHIMGINE

There total 4 articles about TSCHIMGINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.8%

[(1S)-endo]-borneyl 4-benzyloxybenzoate → [(1S)-endo]-borneyl 4-hydroxybenzoate (38970-50-2)

Guidance literature:

With palladium on activated charcoal; hydrogen; In ethyl acetate; at 20 ℃; for 2h; atmospheric pressure;

DOI:10.1021/ma0349433

Reference yield:

Ethyl 4-hydroxybenzoate (120-47-8) → [(1S)-endo]-borneyl 4-hydroxybenzoate (38970-50-2)

Guidance literature:

Multi-step reaction with 4 steps

1: 97 percent / potassium carbonate / acetone / 48 h / 20 °C

2: 93 percent / potassium hydroxide / ethanol / 4 h / Heating

3: 69.4 percent / 1,3-dicyclohexylcarbodiimine; p-toluenesulfonic acid; 4-(dimethylamino)pyridine / CH₂Cl₂ / 20 °C

4: 96.8 percent / H₂; palladium/carbon / ethyl acetate / 2 h / 20 °C / atmospheric pressure

With dmap; potassium hydroxide; palladium on activated charcoal; hydrogen; potassium carbonate; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; In ethanol; dichloromethane; ethyl acetate; acetone;

DOI:10.1021/ma0349433

Reference yield:

p-(benzyloxy)benzoic acid (1486-51-7) → [(1S)-endo]-borneyl 4-hydroxybenzoate (38970-50-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 69.4 percent / 1,3-dicyclohexylcarbodiimine; p-toluenesulfonic acid; 4-(dimethylamino)pyridine / CH₂Cl₂ / 20 °C

2: 96.8 percent / H₂; palladium/carbon / ethyl acetate / 2 h / 20 °C / atmospheric pressure

With dmap; palladium on activated charcoal; hydrogen; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; In dichloromethane; ethyl acetate;

DOI:10.1021/ma0349433

upstream raw materials:

Ethyl 4-hydroxybenzoate

p-(benzyloxy)benzoic acid

ethyl 4-(benzyloxy)benzoate

Downstream raw materials:

isoborneol

4-hydroxy-benzoic acid

Refernces