Dextiopronin

Base Information

• Chemical Name: Dextiopronin
• CAS No.: 29335-92-0
• Molecular Formula: C₅H₉NO₃S
• Molecular Weight: 163.197
• Mol file: 29335-92-0.mol

Synonyms:Glycine,N-(2-mercapto-1-oxopropyl)-, (R)-; Glycine, N-(D-2-mercaptopropionyl)- (8CI);(R)-Tiopronin; (R)-a-Mercaptopropionylglycine; Dextiopronin

Chemical Property of Dextiopronin

Chemical Property:

• Vapor Pressure: 3.6E-08mmHg at 25°C
• Boiling Point: 418.3°Cat760mmHg
• Flash Point: 206.8°C
• PSA: 105.20000
• Density: 1.294g/cm³
• LogP: -0.10360

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (R)-Tiopronin can be used to preapre anti-hepatitis C drugs.

Technology Process of Dextiopronin

There total 1 articles about Dextiopronin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-((R)-2-chloro-propionyl)-glycine (85038-45-5) → tiopronin (29335-92-0)

Guidance literature:

N-((R)-2-chloro-propionyl)-glycine; With sodium disulfide; sodium carbonate; In water; at 0 - 15 ℃;

With sulfuric acid; In water; pH=~ 1;

With zinc; In water; for 3h;

Reference yield:

tiopronin (29335-92-0) → R-(-)-N-(α-mercaptopropionyl)glycine sodium (1007216-16-1)

Guidance literature:

tiopronin; With diothiothreitol; In methanol; at 15 ℃; for 0.25h;

With sodium hydroxide; at 15 - 25 ℃; Molecular sieve;

upstream raw materials:

N-((R)-2-chloro-propionyl)-glycine

Downstream raw materials:

R-(-)-N-(α-mercaptopropionyl)glycine sodium

Refernces