(2S)-2-Amino-3-dimethylaminopropanoic acid

Base Information

• Chemical Name: (2S)-2-Amino-3-dimethylaminopropanoic acid
• CAS No.: 10138-99-5
• Molecular Formula: C5H12N2O2
• Molecular Weight: 132.161
• Hs Code.: 2922499990
• Mol file: 10138-99-5.mol

Synonyms:Propionicacid, 2-amino-3-(dimethylamino)-, L- (8CI);L-4-Azaleucine;b-(Dimethylamino)alanine;b-Dimethylamino-L-alanine;2-Amino-3-(dimethylamino)propionic acid;

Chemical Property of (2S)-2-Amino-3-dimethylaminopropanoic acid

Chemical Property:

• Vapor Pressure: 0.0609mmHg at 25°C
• Refractive Index: 1.492
• Boiling Point: 214.3 °C at 760 mmHg
• PKA: 1.86±0.10(Predicted)
• Flash Point: 83.4 °C
• PSA: 66.56000
• Density: 1.129 g/cm³
• LogP: -0.33980

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-(Dimethylamino)-L-alanine 2HCl 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2S)-2-Amino-3-dimethylaminopropanoic acid

There total 1 articles about (2S)-2-Amino-3-dimethylaminopropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-dimethylammonium chloride (506-59-2) → (R)-2-amino-3-(dimethylamino)propanoic acid (206559-98-0,28024-66-0) + (S)-2-amino-3-(dimethylamino)propanoic acid (10138-99-5,28024-66-0)

Guidance literature:

With hydrogenchloride; potassium carbonate; Yield given. Multistep reaction; 1.) 50 deg C;

DOI:10.1016/S0040-4020(01)86056-7

Reference yield:

methyl 4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-(chlorocarbonyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)benzoate (1351278-78-8) + (S)-2-amino-3-(dimethylamino)propanoic acid (10138-99-5,28024-66-0) → C43H62N2O5

Guidance literature:

With dmap; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; Solvent; Reagent/catalyst; Inert atmosphere;

DOI:10.1016/j.bmcl.2016.03.019

upstream raw materials:

N,N-dimethylammonium chloride

Refernces