Phosphinic acid, diphenyl-, 2-methylpropyl ester

Base Information

• Chemical Name: Phosphinic acid, diphenyl-, 2-methylpropyl ester
• CAS No.: 10122-98-2
• Molecular Formula: C16H19O2P
• Molecular Weight: 274.299
• Mol file: 10122-98-2.mol

Synonyms:diphenyl-phosphinic acid isobutyl ester;isobutyl diphenylphosphonate;Diphenyl-phosphinsaeure-isobutylester;Phosphinic acid,diphenyl-,2-methylpropyl ester;Diphenylphosphonsaeure-isobutylester;

Chemical Property of Phosphinic acid, diphenyl-, 2-methylpropyl ester

Chemical Property:

• Melting Point: 77 °C
• Boiling Point: 372.4±25.0 °C(Predicted)
• PSA: 36.11000
• Density: 1.10±0.1 g/cm3(Predicted)
• LogP: 3.58810

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phosphinic acid, diphenyl-, 2-methylpropyl ester

There total 8 articles about Phosphinic acid, diphenyl-, 2-methylpropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-methyl-propan-1-ol (78-83-1) + diphenyl-phosphinic acid (1707-03-5) → O-isobutyl phenylphenylphosphinate (10122-98-2)

Guidance literature:

With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; In 1,2-dichloro-ethane; at 20 ℃; for 12h; Schlenk technique; Inert atmosphere;

Reference yield: 76.0%

bromobenzene (108-86-1,52753-63-6) + 2-methylpropyl phenylphosphinate (13336-52-2) → O-isobutyl phenylphenylphosphinate (10122-98-2)

Guidance literature:

With palladium diacetate; triethylamine; In neat (no solvent); at 150 ℃; for 0.0833333h; Microwave irradiation;

DOI:10.1039/c4ra03292f

Reference yield: 59.0%

2-methyl-propan-1-ol (78-83-1) + Diphenylphosphine oxide (4559-70-0) → O-isobutyl phenylphenylphosphinate (10122-98-2)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; In acetonitrile; at 20 ℃; for 12h; Electrochemical reaction;

DOI:10.1021/acs.joc.8b02882

upstream raw materials:

sodium isobutoxide

chloro-diphenylphosphine

2-methyl-propan-1-ol

Diphenylphosphine oxide

Refernces

• 1、 Shi, Enxue,Pei, Chengxin. "Pseudohalogenation of phosphites". . p. 2995 - 2998. Retrieved 2004.
• 2、 Deng, Lingling,Wang, Yang,Mei, Haibo,Pan, Yi,Han, Jianlin. "Electrochemical Dehydrogenative Phosphorylation of Alcohols for the Synthesis of Organophosphinates". . p. 949 - 956. Retrieved 2019/01/14.