2-(1-Methyl-9h-carbazol-2-yl)ethanamine

Base Information Edit

Chemical Name:2-(1-Methyl-9h-carbazol-2-yl)ethanamine
CAS No.:5531-70-4
Molecular Formula:C15H16N2
Molecular Weight:224.3009
Hs Code.:
NSC Number:81703
DSSTox Substance ID:DTXSID60292323
Wikidata:Q82030588
ChEMBL ID:CHEMBL1418814
Mol file:5531-70-4.mol

Synonyms:5531-70-4;MLS000737093;2-(1-methyl-9h-carbazol-2-yl)ethanamine;NSC81703;NCIOpen2_004429;CHEMBL1418814;DTXSID60292323;NSC-81703;SMR000528368

Suppliers and Price of 2-(1-Methyl-9h-carbazol-2-yl)ethanamine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(1-Methyl-9h-carbazol-2-yl)ethanamine Edit

Chemical Property:

Vapor Pressure:4.62E-08mmHg at 25°C
Boiling Point:443.5°C at 760 mmHg
Flash Point:252.3°C
Density:1.188g/cm³
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:224.131348519
Heavy Atom Count:17
Complexity:266

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC2=C1NC3=CC=CC=C23)CCN

Technology Process of 2-(1-Methyl-9h-carbazol-2-yl)ethanamine

There total 20 articles about 2-(1-Methyl-9h-carbazol-2-yl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 2-(2-azidoethyl)-1-methyl-9H-carbazole

: 5531-70-4
2-(1-methyl-9H-carbazol-2-yl)ethan-1-amine

Guidance literature:: With platinum(IV) oxide; hydrogen; In methanol; at 20 ℃; for 6h;
DOI:10.1021/acs.joc.9b00706

Reference yield:

: 100880-19-1
2-(1-methyl-9H-carbazol-2-yl)acetonitrile

: 5531-70-4
2-(1-methyl-9H-carbazol-2-yl)ethan-1-amine

Guidance literature:: With sodium tetrahydroborate; In methanol; at 0 ℃; for 0.5h;
DOI:10.1021/jo00302a013

Reference yield:

: 101283-44-7
1-Methyl-9H-carbazol-2-carbonsaeure-ethylester

: 5531-70-4
2-(1-methyl-9H-carbazol-2-yl)ethan-1-amine

Guidance literature:: Multi-step reaction with 4 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 - 20 °C / Schlenk technique; Inert atmosphere

2.1: triethylamine / 0.08 h / 0 °C / Schlenk technique; Inert atmosphere

2.2: 0.17 h / 0 °C / Schlenk technique; Inert atmosphere

3.1: 2 h / 0 - 20 °C / Schlenk technique; Inert atmosphere

4.1: cobalt(II) chloride; sodium tetrahydroborate / methanol / 0.5 h / 0 °C / Schlenk technique; Inert atmosphere

With sodium tetrahydroborate; lithium aluminium tetrahydride; triethylamine; cobalt(II) chloride; In tetrahydrofuran; methanol;
DOI:10.1021/ol5025053