Technology Process of Isoginkgetin
There total 8 articles about Isoginkgetin which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: iodine / dimethyl sulfoxide / 16 h / 100 °C / Inert atmosphere
2: palladium (II) [1,1'-bis(diphenylphosphanyl)ferrocene] dichloride; anhydrous potassium acetate / N,N-dimethyl-formamide / 5 h / 80 °C / Inert atmosphere; Sealed tube
3: sodium hydroxide; tetrakis-(triphenylphosphine)-palladium / N,N-dimethyl-formamide; water monomer / 80 °C / Inert atmosphere; Sealed tube; Microwave irradiation
4: palladium 10% on activated carbon; hydrogen; palladium hydroxide on carbon / dichloromethane; methanol / 5 h / 20 °C
With
palladium (II) [1,1'-bis(diphenylphosphanyl)ferrocene] dichloride; tetrakis-(triphenylphosphine)-palladium; palladium 10% on activated carbon; palladium hydroxide on carbon; hydrogen; iodine; anhydrous potassium acetate; sodium hydroxide;
In
methanol; dichloromethane; water monomer; dimethyl sulfoxide; N,N-dimethyl-formamide;
2: |Miyaura Borylation Reaction / 3: |Suzuki-Miyaura Coupling;
DOI:10.1021/acs.jmedchem.1c01654
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium hydroxide; tetrakis-(triphenylphosphine)-palladium / N,N-dimethyl-formamide; water monomer / 80 °C / Inert atmosphere; Sealed tube; Microwave irradiation
2: palladium 10% on activated carbon; hydrogen; palladium hydroxide on carbon / dichloromethane; methanol / 5 h / 20 °C
With
tetrakis-(triphenylphosphine)-palladium; palladium 10% on activated carbon; palladium hydroxide on carbon; hydrogen; sodium hydroxide;
In
methanol; dichloromethane; water monomer; N,N-dimethyl-formamide;
1: |Suzuki-Miyaura Coupling;
DOI:10.1021/acs.jmedchem.1c01654
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium hydroxide; tetrakis-(triphenylphosphine)-palladium / N,N-dimethyl-formamide; water monomer / 80 °C / Inert atmosphere; Sealed tube; Microwave irradiation
2: palladium 10% on activated carbon; hydrogen; palladium hydroxide on carbon / dichloromethane; methanol / 5 h / 20 °C
With
tetrakis-(triphenylphosphine)-palladium; palladium 10% on activated carbon; palladium hydroxide on carbon; hydrogen; sodium hydroxide;
In
methanol; dichloromethane; water monomer; N,N-dimethyl-formamide;
1: |Suzuki-Miyaura Coupling;
DOI:10.1021/acs.jmedchem.1c01654