N-(p-Tolyl)trichloroacetamide

Base Information

• Chemical Name: N-(p-Tolyl)trichloroacetamide
• CAS No.: 2564-09-2
• Molecular Formula: C9H8Cl3NO
• Molecular Weight: 252.528
• Hs Code.: 2924299090
• Mol file: 2564-09-2.mol

Synonyms:trichloro-acetic acid p-toluidide;N-(4-Methylphenyl)trichloracetamid;2,2,2-trichloro-N-p-tolyl-acetamide;Acetamide,2,2,2-trichloro-N-(4-methylphenyl);Trichloracet-p-toluidid;Acetamide,2,2-trichloro-N-(4-methylphenyl);Trichlor-essigsaeure-p-toluidid;N-(p-Tolyl)trichloroacetamide;N-(4-methylphenyl)-2,2,2,-trichloroacetamide;

Chemical Property of N-(p-Tolyl)trichloroacetamide

Chemical Property:

• Vapor Pressure: 0.000115mmHg at 25°C
• Boiling Point: 336°C at 760 mmHg
• Flash Point: 157°C
• PSA: 29.10000
• Density: 1.459g/cm³
• LogP: 3.37670

Purity/Quality:

98%min ^*data from raw suppliers

2,2,2-TRICHLORO-N-(4-METHYLPHENYL)ACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(p-Tolyl)trichloroacetamide

There total 4 articles about N-(p-Tolyl)trichloroacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1,1,1,3,3,3-hexachloro-propan-2-one (116-16-5) + p-toluidine (106-49-0,12221-03-3) → N-(4-methylphenyl)-2,2,2,-trichloroacetamide (2564-09-2)

Guidance literature:

In chloroform; for 3h; Heating;

Reference yield:

p-toluidine (106-49-0,12221-03-3) + trifluoroacetyl chloride (76-02-8) → N-(4-methylphenyl)-2,2,2,-trichloroacetamide (2564-09-2)

Guidance literature:

With diethyl ether;

Reference yield:

trichloroacetic acid (76-03-9) → N-(4-methylphenyl)-2,2,2,-trichloroacetamide (2564-09-2)

Guidance literature:

With trichlorophosphate; Darstellung; man verduennt dann mit Benzol und fuegt p-Toluidin bis zum Aufhoeren der Erwaermung hinzu;

upstream raw materials:

1,1,1,3,3,3-hexachloro-propan-2-one

p-toluidine

trifluoroacetyl chloride

trichloroacetic acid

Downstream raw materials:

N,N'-Di-p-tolyloxalamide

N-(4-methylphenyl)-N'-(6-nitrobenzothiazol-2-yl)urea

N-(4-methylphenyl)-N'-(6-chlorobenzothiazol-2-yl)urea

methyl p-tolylcarbamate

Refernces

• 1、 Bew, Clive,Joshi, Virginia Otero de,Gray, Jim,Kaye, Perry T.,Meakins, G. Denis. "Formation of N-Substituted Trichloroacetamides from Amines and Hexachloroacetone". . p. 945 - 948. Retrieved 2007/10/02.