Chemical Property of Lochnericine
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Chemical Property:
- Vapor Pressure:3.6E-10mmHg at 25°C
- Melting Point:190-3°C (dec.).
- Boiling Point:501°C at 760 mmHg
- PKA:pKa in 66% DMF: 4.2(at 25℃)
- Flash Point:256.8°C
- PSA:54.10000
- Density:1.35g/cm3
- LogP:2.50830
- XLogP3:2.5
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:5
- Rotatable Bond Count:3
- Exact Mass:352.17869263
- Heavy Atom Count:26
- Complexity:705
- Purity/Quality:
-
98%Min *data from raw suppliers
Lochnericine ≥98% *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CCC12CC(=C3C4(C1N(CC4)CC5C2O5)C6=CC=CC=C6N3)C(=O)OC
- Isomeric SMILES:CC[C@]12CC(=C3[C@@]4([C@H]1N(CC4)C[C@H]5[C@@H]2O5)C6=CC=CC=C6N3)C(=O)OC
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Description
One of the numerous alkaloids which have been isolated from Vinca rosea L.
(Syn. Catharanthus roseus G. Don.), this base yields colourless crystals from
MeOH and is strongly laevorotatory with [α]D - 528° (CHCl3) or [α]27D - 432°
(CHCI3). The ultraviolet spectrum of the alkaloid in EtOH shows three absorption maxima at 226, 297 and 327 ffi/.l. The suggested structure contains one
methoxycarbonyl group, an imino group, a bridge ethyl group and an epoxy
ring. The second nitrogen atom is tertiary.