4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester

Base Information Edit

Chemical Name:4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester
CAS No.:110962-94-2
Molecular Formula:C19H18Cl2N2O4
Molecular Weight:409.269
Hs Code.:2933399090
UNII:77AD3HZ6QG
Nikkaji Number:J1.229.136A
Mol file:110962-94-2.mol

Synonyms:110962-94-2;4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester;3-(2-CYANOETHYL) 5-METHYL 4-(2,3-DICHLOROPHENYL)-2,6-DIMETHYL-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLATE;5-O-(2-cyanoethyl) 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;3,5-pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, 2-cyanoethyl methyl ester;77AD3HZ6QG;SCHEMBL820500;AMY23239;FT-0731803;F19502;3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, 3-(2-cyanoethyl) 5-methyl ester (;3-(2-Cyanoethyl) 5-methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate;4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylicacid3-(2-cyano-ethyl)ester5-methylester;Clevidipine Butyrate iMpurity;3-(2-cyanoethyl) 5-Methyl 4-(2',3'-dichlorophenyl)-2,6-diMethyl-1,4-dihydropyridine-3,5-dicarboxylate

Suppliers and Price of 4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-PyridinedicarboxylicAcid2-cyanoethylMethylEster
10mg
$ 1320.00

TRC
4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-PyridinedicarboxylicAcid2-cyanoethylMethylEster
1mg
$ 165.00

Total 33 raw suppliers

Chemical Property of 4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester Edit

Chemical Property:

Boiling Point:552.6±50.0 °C(Predicted)
PKA:2.54±0.70(Predicted)
PSA：88.42000
Density:1.317±0.06 g/cm3(Predicted)
LogP:4.18688
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:408.0643624
Heavy Atom Count:27
Complexity:723

Purity/Quality:

98%, ^*data from raw suppliers

4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-PyridinedicarboxylicAcid2-cyanoethylMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(C(=C(N1)C)C(=O)OCCC#N)C2=C(C(=CC=C2)Cl)Cl)C(=O)OC
Uses 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-Pyridinedicarboxylic Acid 2-cyanoethyl Methyl Ester, is an impurity of Amlodipine (A633495), a dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.

Technology Process of 4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester

There total 6 articles about 4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.5%