4-Amino-2,3-xylenol

Base Information

• Chemical Name: 4-Amino-2,3-xylenol
• CAS No.: 3096-69-3
• Molecular Formula: C8H11NO
• Molecular Weight: 137.181
• Hs Code.: 2922299090
• European Community (EC) Number: 221-446-4
• NSC Number: 143549
• DSSTox Substance ID: DTXSID70184947
• Nikkaji Number: J80.637D
• Wikidata: Q83055892
• Mol file: 3096-69-3.mol

Synonyms:2,6-dimethylacetaminophen;2,6-DM-APAP;4-hydroxyxylidine

Chemical Property of 4-Amino-2,3-xylenol

Chemical Property:

• Vapor Pressure: 0.00082mmHg at 25°C
• Melting Point: 174oC
• Refractive Index: 1.6
• Boiling Point: 296.3 °C at 760 mmHg
• Flash Point: 133 °C
• PSA: 46.25000
• Density: 1.118 g/cm³
• LogP: 2.17240
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: soluble in Methanol
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 137.084063974
• Heavy Atom Count: 10
• Complexity: 116

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Amino-2,3-dimethylphenol ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CC(=C1C)O)N

Technology Process of 4-Amino-2,3-xylenol

There total 10 articles about 4-Amino-2,3-xylenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,3-dimethyl-4-nitrophenol (19499-93-5) → 4-amino-2,3-dimethylphenol (3096-69-3)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In ethanol; at 20 ℃; for 5h;

Reference yield: 78.0%

1-hydroxy-2,3-dimethyl-4-nitrosobenzene (74783-54-3) → 4-amino-2,3-dimethylphenol (3096-69-3)

Guidance literature:

With hydrogen sulfide; ammonia; In water;

Reference yield:

2,3-dimethylnitrobenzene (83-41-0) → 4-amino-2,3-dimethylphenol (3096-69-3)

Guidance literature:

With sulfuric acid; In ethanol; at 90 ℃; (electrochemical reduction);

upstream raw materials:

4-diazobenzenesulfonic acid

2,3-Dimethylphenol

2,3-Dimethyl-4-phenylazo-phenol

2,3-dimethylnitrobenzene

Downstream raw materials:

2,3-dimethyl-1,4-benzoquinone

2,3-Dimethylhydroquinone monomethyl ether

N-(4-hydroxy-2,3-dimethyl-phenyl)acetamide

2,3-Dimethyl-4-tosylaminophenol

Refernces

• 1、 -. "IMIDAZO[4,5-B]PYRIDIN-2-ONE AND OXAZOLO[4,5-B]PYRIDIN-2-ONE COMPOUNDS AND ANALOGS THEREOF AS THERAPEUTIC COMPOUNDS". Page/Page column 176. . Retrieved 2008/06/13.
• 2、 -. "Hair colouring and conditioning compositions". . . Retrieved 2008/06/13.