Benzeneacetic acid, 1-pyrenylmethyl ester

Base Information

• Chemical Name: Benzeneacetic acid, 1-pyrenylmethyl ester
• CAS No.: 111077-45-3
• Molecular Formula: C25H18O2
• Molecular Weight: 350.417
• Mol file: 111077-45-3.mol

Synonyms:

Chemical Property of Benzeneacetic acid, 1-pyrenylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzeneacetic acid, 1-pyrenylmethyl ester

There total 3 articles about Benzeneacetic acid, 1-pyrenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyrene-1-aldehyde (3029-19-4) → 1-pyrenylmethyl ester of phenylacetic acid (111077-45-3)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrazine hydrate / diethyl ether / 0 °C

2: 88 percent / mercuric oxide, methanolic potassium hydroxide / diethyl ether

3: dimethylformamide

With potassium hydroxide; hydrazine hydrate; mercury(II) oxide; In diethyl ether; N,N-dimethyl-formamide;

DOI:10.1016/S0040-4039(00)95811-8

Reference yield:

1-pyrenecarboxaldehyde hydrazone (76465-53-7) → 1-pyrenylmethyl ester of phenylacetic acid (111077-45-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / mercuric oxide, methanolic potassium hydroxide / diethyl ether

2: dimethylformamide

With potassium hydroxide; mercury(II) oxide; In diethyl ether; N,N-dimethyl-formamide;

DOI:10.1016/S0040-4039(00)95811-8

Reference yield:

phenylacetic acid (103-82-2) + pyrenyl-1-diazomethane (78377-23-8) → 1-pyrenylmethyl ester of phenylacetic acid (111077-45-3)

Guidance literature:

In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4039(00)95811-8

upstream raw materials:

phenylacetic acid

pyrenyl-1-diazomethane

pyrene-1-aldehyde

1-pyrenecarboxaldehyde hydrazone

Downstream raw materials:

phenylacetic acid

methyl 1-pyrenylmethyl ether

Refernces