1,4-Butanediamine, 2-methyl-, dihydrochloride

Base Information

• Chemical Name: 1,4-Butanediamine, 2-methyl-, dihydrochloride
• CAS No.: 111469-11-5
• Molecular Formula: C5H14N2.2ClH
• Molecular Weight: 175.101
• Hs Code.: 2921290000
• Mol file: 111469-11-5.mol

Synonyms:(+-)-2-methyl-butane-1,4-diyldiamine,hydrochloride;(+-)-2-Methyl-butan-1,4-diyldiamin,Hydrochlorid;(+-)-2'-Methyl-benzoin;Ethanone,2-hydroxy-2-(2-methylphenyl)-1-phenyl;

Chemical Property of 1,4-Butanediamine, 2-methyl-, dihydrochloride

Chemical Property:

• PSA: 52.04000
• LogP: 2.93460

Purity/Quality:

98%min ^*data from raw suppliers

2-Methylbutane-1,4-diamine dihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,4-Butanediamine, 2-methyl-, dihydrochloride

There total 12 articles about 1,4-Butanediamine, 2-methyl-, dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-methyl-1,4-bis<(benzyloxycarbonyl)amino>butane (111469-06-8) → (+/-)-2-methyl-butane-1,4-diyldiamine; hydrochloride (111469-11-5)

Guidance literature:

With hydrogenchloride; hydrogen; platinum(IV) oxide; In ethanol; for 18h; under 2585.7 Torr;

DOI:10.1021/jo00237a032

Reference yield:

ethyl 4-formylpyrrole-2-carboxylate (7126-57-0) → (+/-)-2-methyl-butane-1,4-diyldiamine; hydrochloride (111469-11-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 90 percent / 10percent Pd/C / ethanol / 16 h / 2585.7 Torr

2: 73 percent / KOH / ethane-1,2-diol / 200 °C

4: 95 percent / H₂, concd HCl / PtO₂ / ethanol / 18 h / 2585.7 Torr

With hydrogenchloride; potassium hydroxide; hydrogen; platinum(IV) oxide; palladium on activated charcoal; In ethanol; ethylene glycol;

DOI:10.1021/jo00237a032

Reference yield:

3-methylpyrrole (616-43-3) → (+/-)-2-methyl-butane-1,4-diyldiamine; hydrochloride (111469-11-5)

Guidance literature:

Multi-step reaction with 2 steps

2: 95 percent / H₂, concd HCl / PtO₂ / ethanol / 18 h / 2585.7 Torr

With hydrogenchloride; hydrogen; platinum(IV) oxide; In ethanol;

DOI:10.1021/jo00237a032

upstream raw materials:

2-methyl-1,4-bis<(benzyloxycarbonyl)amino>butane

3-methylpyrrole

methyl 1H-pyrrole-3-carboxylate

pyrrole-3-carboxylic acid hydrazide

Downstream raw materials:

2-methyl-1,4-butandiol

Refernces

• 1、 Kojima, Masaaki,Morita, Ken'ichi,Fujita, Junnosuke. "Preparation and Spectroscopic Studies of Cobalt(III) Complexes Containing Optically Active Seven-membered Chelate Ligands". . p. 2947 - 2955. Retrieved 2007/10/02.