Triethyl 4-phosphonocrotonate

Base Information Edit

Chemical Name:Triethyl 4-phosphonocrotonate
CAS No.:10236-14-3
Molecular Formula:C10H19O5P
Molecular Weight:250.232
Hs Code.:29319090
European Community (EC) Number:623-775-2,868-050-3
NSC Number:100748
Nikkaji Number:J1.008.026F,J149.943B
Wikidata:Q76305368
Mol file:10236-14-3.mol

Synonyms:Triethyl 4-phosphonocrotonate;10236-14-3;42516-28-9;(E)-Ethyl 4-(diethoxyphosphoryl)but-2-enoate;ethyl 4-(diethoxyphosphoryl)but-2-enoate;ethyl (E)-4-diethoxyphosphorylbut-2-enoate;ethyl (2E)-4-(diethyl phosphono)but-2-enoate;Triethyl .gamma.-phosphonocrotonate;TRIETHYL 4-PHOSPHONOCROTONATEDISC 6/01;NSC100748;Ethyl 4-(diethylphosphono)crotonate;ethyl (2E)-4-(diethoxyphosphoryl)but-2-enoate;SCHEMBL687973;ethyl 4-diethylphosphonocrotonate;MFCD00009192;AKOS015907698;GS-6352;NSC-100748;ethyl 4-(diethyl phosphono)but-2-enoate;trans-Ethyl-4-(diethylphosphono)crotonate;Triethyl 4-phosphonocrotonate, cis + trans;(E)-Ethyl4-(diethoxyphosphoryl)but-2-enoate;CS-0132407;CS-0356393;4-(Diethoxyphosphinyl)crotonic acid ethyl ester;diethyl 3-ethoxycarbonyl-2-propenylphos-phonate;EN300-198195;Ethyl (E)-4-(diethoxyphosphoryl)but-2-enoate;H10406;EN300-6734692;A896819;diethyl (E)-3-ethoxycarbonyl-2-propenylphosphonate;Ethyl (2E)-4-(diethoxyphosphoryl)-2-butenoate #;2-Butenoic acid,4-(diethoxyphosphinyl)-,ethyl ester;4-(Diethoxyphosphinyl)-2-butenoic acid ethyl ester;J-000677;2-Butenoic acid, 2-(diethoxyphosphinyl)-, ethyl ester

Suppliers and Price of Triethyl 4-phosphonocrotonate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Ethyl 4-(diethoxyphosphoryl)crotonate 94%
1 g
$ 104.00

Sigma-Aldrich
Triethyl 4-phosphonocrotonate, mixture of isomers technical grade, 90%
10g
$ 106.00

Matrix Scientific
Triethyl 4-phosphonocrotonate 90+%
25g
$ 158.00

Matrix Scientific
Triethyl 4-phosphonocrotonate 90+%
5g
$ 56.00

Frontier Specialty Chemicals
Triethyl4-phosphonocrotonate,92%,predominantlytrans
10g
$ 100.00

Frontier Specialty Chemicals
Triethyl4-phosphonocrotonate,92%,predominantlytrans
50g
$ 408.00

Biosynth Carbosynth
4-(Diethoxyphosphinyl)-2-butenoic acid ethyl ester
10 g
$ 160.00

Biosynth Carbosynth
4-(Diethoxyphosphinyl)-2-butenoic acid ethyl ester
25 g
$ 287.50

Biosynth Carbosynth
4-(Diethoxyphosphinyl)-2-butenoic acid ethyl ester
50 g
$ 475.00

Biosynth Carbosynth
4-(Diethoxyphosphinyl)-2-butenoic acid ethyl ester
2 g
$ 50.00

Total 33 raw suppliers

Chemical Property of Triethyl 4-phosphonocrotonate Edit

Chemical Property:

Appearance/Colour:clear colorless liquid
Vapor Pressure:0.000204mmHg at 25°C
Refractive Index:n20/D 1.455(lit.)
Boiling Point:352.9 °C at 760 mmHg
Flash Point:167.6 °C
PSA：71.64000
Density:1.099 g/cm³
LogP:2.37180
XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:250.09701070
Heavy Atom Count:16
Complexity:264

Purity/Quality:

98%,99%, ^*data from raw suppliers

Ethyl 4-(diethoxyphosphoryl)crotonate 94% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-37/39-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCOC(=O)C=CCP(=O)(OCC)OCC
Isomeric SMILES:CCOC(=O)/C=C/CP(=O)(OCC)OCC
Uses Triethyl 4-phosphonocrotonate is used as a reactant for iminodipropionic acid as a leaving group for DNA polymerization by HIV-1 reverse transcriptase, orally bioavailable GPR40 agonist synthesis, preparation of mGlu4R agonists and synthesis of fluoroketone inhibitors of group VIA calcium-independent phospholipase A2. Reactant for: Iminodipropionic acid as a leaving group for DNA polymerization by HIV-1 reverse transcriptaseStereoselective preparation of C1-C19 fragment of macrolide antibiotic aplyronine A using diastereoselective Nozaki-Hiyama-Kishi coupling reactionsOrally bioavailable GPR40 agonist synthesisSynthesis of fluoroketone inhibitors of group VIA calcium-independent phospholipase A2Preaparation of mGlu4R agonistsDearomatizing cyclization of nicotinyl-substituted esters and ketones

Technology Process of Triethyl 4-phosphonocrotonate

There total 2 articles about Triethyl 4-phosphonocrotonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%