Perphenazine sulfoxide

Base Information Edit

Chemical Name:Perphenazine sulfoxide
CAS No.:10078-25-8
Molecular Formula:C21H26 Cl N3 O2 S
Molecular Weight:419.97
Hs Code.:2934305050
UNII:5S6Q9MQ62M
DSSTox Substance ID:DTXSID70905735
Nikkaji Number:J50.618D
Wikidata:Q27262799
Mol file:10078-25-8.mol

Synonyms:Perphenazine sulfoxide;10078-25-8;BRN 1230223;UNII-5S6Q9MQ62M;PERPHENAZINE SULFOXIDE (100 MG);5S6Q9MQ62M;2-[4-[3-[(5R)-2-chloro-5-oxophenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;Perphenazine Sulphoxide;2-Chloro-10-(3-(4-(2-hydroxyethyl)-7-piperazinyl)propyl)phenothiazine;1-Piperazineethanol, 4-(3-(2-chlorophenothiazin-10-yl)propyl)-, sulfoxide;C21H26ClN3O2S;2-[4-[3-(2-chloro-5-oxophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol;1-PIPERAZINEETHANOL, 4-(3-(2-CHLORO-10H-PHENOTHIAZIN-10-YL)PROPYL)-, S-OXIDE;1-Piperazineethanol, 4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-, S-oxide;2-[4-[3-(2-Chloro-5-oxido-10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethanol (Perphenazine Sulphoxide);ETHAPERAZINE SULFOXIDE;Perphenazine sulfoxide(100 mg);DTXSID70905735;C21-H26-Cl-N3-O2-S;PERPHENAZINE SULFOXIDE [USP-RS];PERPHENAZINE SULFOXIDE, (+/-)-;LS-112193;PERPHENAZINE IMPURITY A [EP IMPURITY];PERPHENAZINE SULFOXIDE [USP IMPURITY];Perphenazine Sulphoxide 1.0 mg/ml in Methanol;Q27262799;1-Piperazineethanol, 4-[3-(2-chlorophenothiazin-10-yl)propyl]-, S-oxide;1-PIPERAZINEETHANOL, 4-(3-(2-CHLORO-5-OXIDO-10H-PHENOTHIAZIN-10-YL)PROPYL)-;2-(4-(3-(2-CHLORO-5-OXIDO-10H-PHENOTHIAZIN-10-YL)PROPYL)PIPERAZIN-1-YL)ETHANOL;2-{4-[3-(2-chloro-5-oxido-10H-phenothiazin-10-yl)propyl]-1-piperazinyl}ethanol;Cyclohexaneacetic acid, .alpha.-[[(phenylmethoxy)carbonyl]amino]-, (.alpha.S)-;2-Chloro-10-{3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl}-5lambda~4~-phenothiazin-5(10H)-one

Suppliers and Price of Perphenazine sulfoxide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Perphenazine sulfoxide
250mg
$ 1390.00

Sigma-Aldrich
Perphenazine sulfoxide
100mg
$ 1160.00

Medical Isotopes, Inc.
PerphenazineSulfate
250 mg
$ 2200.00

Medical Isotopes, Inc.
PerphenazineSulfate
25 mg
$ 650.00

American Custom Chemicals Corporation
PERPHENAZINE SULFOXIDE 95.00%
5MG
$ 502.83

Total 9 raw suppliers

Chemical Property of Perphenazine sulfoxide Edit

Chemical Property:

Vapor Pressure:1.78E-16mmHg at 25°C
Melting Point:144-145 °C
Boiling Point:624.8°Cat760mmHg
PKA:14.96±0.10(Predicted)
Flash Point:331.7°C
PSA：66.23000
Density:1.41g/cm³
LogP:3.76470
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:419.1434259
Heavy Atom Count:28
Complexity:532

Purity/Quality:

98%,99%, ^*data from raw suppliers

Perphenazine sulfoxide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCCN2C3=CC=CC=C3S(=O)C4=C2C=C(C=C4)Cl)CCO
Uses Perphenazine Sulfoxide (Perphenazine EP Impurity A) acts as a D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist; phenothiazine antipsychotic. Inhibits glutamate dehydrogenase in vitro. Antipsychotic.

Technology Process of Perphenazine sulfoxide

There total 3 articles about Perphenazine sulfoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%