Methyl n-formyl-3-methoxy-o-methyltyrosinate

Base Information

• Chemical Name: Methyl n-formyl-3-methoxy-o-methyltyrosinate
• CAS No.: 58143-18-3
• Molecular Formula: C13H17NO5
• Molecular Weight: 267.2778
• NSC Number: 121979
• DSSTox Substance ID: DTXSID20298245
• Mol file: 58143-18-3.mol

Synonyms:58143-18-3;methyl n-formyl-3-methoxy-o-methyltyrosinate;NSC121979;DTXSID20298245;NSC-121979

Chemical Property of Methyl n-formyl-3-methoxy-o-methyltyrosinate

Chemical Property:

• Vapor Pressure: 1.09E-08mmHg at 25°C
• Boiling Point: 461.2°Cat760mmHg
• Flash Point: 232.8°C
• Density: 1.163g/cm³
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 7
• Exact Mass: 267.11067264
• Heavy Atom Count: 19
• Complexity: 297

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)CC(C(=O)OC)NC=O)OC

Technology Process of Methyl n-formyl-3-methoxy-o-methyltyrosinate

There total 2 articles about Methyl n-formyl-3-methoxy-o-methyltyrosinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(3,4-dimethoxyphenyl)-2-aminopropionic acid (55-59-4) → N-formyl-3,4-dimethoxy-phenylalanine methyl ester (58143-18-3)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid anhydride

With acetic anhydride;

DOI:10.1021/jo01109a019

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + N-formyl-3,4-dimethoxy-DL-phenylalanine (53053-93-3) → N-formyl-3,4-dimethoxy-phenylalanine methyl ester (58143-18-3)

Guidance literature:

DOI:10.1021/jo01109a019

upstream raw materials:

diazomethane

N-formyl-3,4-dimethoxy-DL-phenylalanine

3-(3,4-dimethoxyphenyl)-2-aminopropionic acid