DL-2,3-DIAMINOPROPANOICACID

Base Information

• Chemical Name: DL-2,3-DIAMINOPROPANOICACID
• CAS No.: 6018-54-8
• Molecular Formula: C₃H₈N₂O₂
• Molecular Weight: 104.109
• Mol file: 6018-54-8.mol

Synonyms:Propionicacid, 2,3-diamino- (6CI,8CI);DL-Alanine, 3-amino-;2,3-Diaminopropanoic acid;2,3-Diaminopropionic acid;2-Amino-b-alanine;DL-2,3-Diaminopropanoicacid;DL-2,3-Diaminopropionic acid;DL-3-Aminoalanine;DL-a,b-Diaminopropionic acid;Propanoic acid, 2,3-diamino-;a,b-Diaminopropionic acid;b-Alanine, 2-amino-;b-Aminoalanine;

Chemical Property of DL-2,3-DIAMINOPROPANOICACID

Chemical Property:

• PSA: 89.34000
• LogP: -0.24240

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of DL-2,3-DIAMINOPROPANOICACID

There total 38 articles about DL-2,3-DIAMINOPROPANOICACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

haloirciniamide A → (S)-2,3-diaminopropionic acid (515-94-6,1915-96-4,4033-39-0,6018-54-8) + L-isoserine (565-71-9,632-11-1,632-12-2,632-13-3) + (2R)-aspartic acid (1783-96-6,25608-40-6,27881-03-4,32505-46-7,52526-39-3)

Guidance literature:

haloirciniamide A; With hydrogenchloride; In water; at 110 ℃; for 15h;

With sodium hydrogencarbonate; N-(2,4-dinitro-5-fluorophenyl)-L-alaninamide; In water; acetone; at 40 ℃; for 1h;

DOI:10.3390/MD18080396

Reference yield:

(11S)-cyclocinamide A (194427-76-4) → (S)-2,3-diaminopropionic acid (515-94-6,1915-96-4,4033-39-0,6018-54-8) + L-isoserine (565-71-9,632-11-1,632-12-2,632-13-3) + L-Aspartic acid (56-84-8,25608-40-6,27881-03-4,32505-46-7,52526-39-3) + 5-bromo-DL-tryptophan (6548-09-0,25197-99-3,93299-40-2)

Guidance literature:

With hydrogenchloride; water; In phenol; at 110 ℃; for 4h; Inert atmosphere;

DOI:10.1021/ol300576n

Reference yield:

coprisamide C → D-Alanine (338-69-2,25191-17-7,18875-37-1) + L-valine (72-18-4,25609-85-2,7004-03-7,921-10-8) + (S)-2,3-diaminopropionic acid (515-94-6,1915-96-4,4033-39-0,6018-54-8) + D-Serine (312-84-5,83245-15-2) + (R)-leucine (328-38-1,21675-61-6,25248-98-0,70-45-1) + (2S,3S)-3-methylaspartic acid (6061-13-8)

Guidance literature:

With hydrogenchloride; In water; at 100 ℃; for 2h;

DOI:10.1021/acs.jnatprod.0c00864

upstream raw materials:

(R)-2,3-bis-(2-chloro-acetylamino)-propionic acid

N^α-Tos-D-A₂pr

(2R)-aspartic acid

L-3-acetyl-amino-2-amino-propionic acid

Downstream raw materials:

L-2-Amino-3-ureido-propanoic acid

(R)-2-Amino-3-(5-amino-6-chloro-pyrimidin-4-ylamino)-propionic acid

(S)-2-Amino-3-(5-amino-6-chloro-pyrimidin-4-ylamino)-propionic acid

N^α,N^β-bis(t-butoxycarbonyl)-L-α,β-diaminopropionic acid

Refernces

• 1、 Fernández, Rogelio,Bayu, Asep,Hadi, Tri Aryono,Bueno, Santiago,Pérez, Marta,Cuevas, Carmen,Putra, Masteria Yunovilsa. "Unique polyhalogenated peptides from the marine sponge Ircinia sp.". . . Retrieved 2020/08/28.
• 2、 Karadeniz, Leman,Astley, Stephen T.. "Catalyst functional group cooperativity in the amino acid-catalysed nitroaldol condensation reaction". . p. 3407 - 3415. Retrieved 2013/09/23.