1,7-BIS(HYDROXYMETHYL)-M-CARBORANE

Base Information

• Chemical Name: 1,7-BIS(HYDROXYMETHYL)-M-CARBORANE
• CAS No.: 23924-78-9
• Molecular Formula: C₄H₁₆B₁₀O₂
• Molecular Weight: 204.28
• Mol file: 23924-78-9.mol

Synonyms:1,7-Bis(hydroxymethyl)-m-carborane

Chemical Property of 1,7-BIS(HYDROXYMETHYL)-M-CARBORANE

Chemical Property:

• PSA: 40.46000
• LogP: -7.35140

Purity/Quality:

98% ^*data from raw suppliers

1,7-BIS(HYDROXYMETHYL)-META-CARBORANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Low toxicity by ingestion. A moderate eye irritant.
• Hazard Codes: Low toxicity by ingestion. A moderate eye irritant.

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,7-BIS(HYDROXYMETHYL)-M-CARBORANE

There total 5 articles about 1,7-BIS(HYDROXYMETHYL)-M-CARBORANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.1%

1.7-(CH2OCOCH3)2-1.7-C2B10H10 (42568-26-3) → 1,7-bis(hydroxymethyl)-m-carborane (23924-78-9)

Guidance literature:

With sulfuric acid; at 50 ℃; for 3h; Reagent/catalyst; Temperature;

Reference yield: 88.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 1,7-dicarba-closo-dodecaborane(12) (16986-24-6) → 1,7-bis(hydroxymethyl)-m-carborane (23924-78-9)

Guidance literature:

1,7-dicarba-closo-dodecaborane⁽¹²⁾; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 3h; Schlenk technique; Inert atmosphere;

formaldehyd; In tetrahydrofuran; hexane; at 0 - 20 ℃; for 27h; Schlenk technique; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; hexane; water; at 0 ℃; Schlenk technique; Inert atmosphere;

DOI:10.1002/pola.27525

Reference yield: 59.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 1,7-dicarba-closo-dodecaborane(12) (16986-24-6) → 1-(hydroxymethyl)-1,7-dicarba-closo-dodecaborane(12) (53257-04-8) + 1,7-bis(hydroxymethyl)-m-carborane (23924-78-9)

Guidance literature:

1,7-dicarba-closo-dodecaborane⁽¹²⁾; With n-butyllithium; In diethyl ether; hexane; benzene; at 0 - 20 ℃; for 1h; Inert atmosphere;

formaldehyd; In diethyl ether; hexane; benzene; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.bmcl.2015.11.068

upstream raw materials:

formaldehyd

dilithio-m-carborane

water

1,7-dicarba-closo-dodecaborane⁽¹²⁾

Refernces

• 1、 Izmaylov, Boris A.,Vasnev, Valerii A.,Markova, Galy D.. "On the reactions of haloidmagnesiummethyl-m-carboranes with organoalkoxysilanes and chlorosilanes". . p. 475 - 480. Retrieved 2018.
• 2、 Tanaka, Tomohiro,Nishiura, Yukiko,Araki, Rikita,Saido, Takaomi,Abe, Ryo,Aoki, Shin. "11B NMR Probes of Copper(II): Finding and Implications of the Cu2+-Promoted Decomposition of ortho-Carborane Derivatives". . p. 1819 - 1834. Retrieved 2016/05/02.