Technology Process of 1H-Thiocino[3,2-b]pyridine-3-carboxylic acid,
4,4a,6,7,8,9-hexahydro-2-methyl-4-(3-nitrophenyl)-, ethyl ester,
5,5-dioxide
There total 8 articles about 1H-Thiocino[3,2-b]pyridine-3-carboxylic acid,
4,4a,6,7,8,9-hexahydro-2-methyl-4-(3-nitrophenyl)-, ethyl ester,
5,5-dioxide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 6.8 g / sodium borohydride / ethanol / 0.5 h
2: 7.5 g / m-chloroperoxybenzoic acid / CHCl3 / 1) 0 deg C, 1h, 2) room temp., 30 min
3: 5.0 g / Jones reagent / acetone
4: tin tetrachloride / diethyl ether / 4 h
5: 45 percent / 10percent sulfuric acid / H2O; methanol / 16 h / Heating
6: BF3 / diethyl ether
7: 10percent sulfuric acid / H2O; methanol / 16 h
8: 556 mg / ethanol / Heating
With
sodium tetrahydroborate; jones reagent; sulfuric acid; boron trifluoride; tin(IV) chloride; 3-chloro-benzenecarboperoxoic acid;
In
methanol; diethyl ether; ethanol; chloroform; water; acetone;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 7.5 g / m-chloroperoxybenzoic acid / CHCl3 / 1) 0 deg C, 1h, 2) room temp., 30 min
2: 5.0 g / Jones reagent / acetone
3: tin tetrachloride / diethyl ether / 4 h
4: 45 percent / 10percent sulfuric acid / H2O; methanol / 16 h / Heating
5: BF3 / diethyl ether
6: 10percent sulfuric acid / H2O; methanol / 16 h
7: 556 mg / ethanol / Heating
With
jones reagent; sulfuric acid; boron trifluoride; tin(IV) chloride; 3-chloro-benzenecarboperoxoic acid;
In
methanol; diethyl ether; ethanol; chloroform; water; acetone;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 45 percent / 10percent sulfuric acid / H2O; methanol / 16 h / Heating
2: BF3 / diethyl ether
3: 10percent sulfuric acid / H2O; methanol / 16 h
4: 556 mg / ethanol / Heating
With
sulfuric acid; boron trifluoride;
In
methanol; diethyl ether; ethanol; water;