Galactinol dihydrate

Base Information

• Chemical Name: Galactinol dihydrate
• CAS No.: 16908-86-4
• Molecular Formula: C₁₂H₂₂O₁₁
• Molecular Weight: 342.3
• DSSTox Substance ID: DTXSID30584969
• Metabolomics Workbench ID: 41511
• Wikidata: Q27160224
• Mol file: 16908-86-4.mol

Synonyms:1-O-(alpha-D-galactopyranosyl)-myo-inositol dihydrate;6 beta-galactinol;galactinol;galactinol dihydrate

Chemical Property of Galactinol dihydrate

Chemical Property:

• Vapor Pressure: 1.99E-25mmHg at 25°C
• Boiling Point: 742.2 °C at 760 mmHg
• PKA: 12.90±0.70(Predicted)
• Flash Point: 402.7 °C
• PSA: 218.99000
• Density: 1.84±0.1 g/cm3(Predicted)
• LogP: -6.13900
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: Water (Sparingly)
• Hydrogen Bond Donor Count: 11
• Hydrogen Bond Acceptor Count: 13
• Rotatable Bond Count: 3
• Exact Mass: 378.13734088
• Heavy Atom Count: 25
• Complexity: 379

Purity/Quality:

99%, ^*data from raw suppliers

IsogalactinolHydrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C1C(C(C(C(O1)OC2C(C(C(C(C2O)O)O)O)O)O)O)O)O.O.O
• Isomeric SMILES: C([C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)OC2[C@@H]([C@H](C([C@H]([C@H]2O)O)O)O)O)O)O)O)O.O.O
• Uses: Galactinol hydrate is a useful disaccharide for proteomics research.

Technology Process of Galactinol dihydrate

There total 8 articles about Galactinol dihydrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.4%

1-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-2,3,4,5,6-penta-O-acetyl-sn-myo-inositol (6587-77-5,6614-32-0,6614-79-5,21024-29-3,34279-93-1,62138-04-9,62138-08-3) → 1-O-α-D-mannopyranosyl-sn-myo-inositol (2347-99-1,3687-64-7,4539-73-5,4572-85-4,4623-85-2,6605-49-8,6614-80-8,16908-86-4,19694-63-4,23567-09-1,34279-92-0,52340-87-1,54422-83-2,62138-03-8,62138-07-2,79391-04-1,89194-80-9,90080-19-6,92418-92-3,136457-84-6,136598-73-7)

Guidance literature:

With sodium hydroxide; In methanol; for 5h;

Reference yield: 67.1%

1-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-3,4,5,6-tetra-O-acetyl-sn-myo-inositol (29971-56-0,29971-57-1,29971-58-2,29971-59-3,130548-64-0,130548-65-1) → 1-O-α-D-mannopyranosyl-sn-myo-inositol (2347-99-1,3687-64-7,4539-73-5,4572-85-4,4623-85-2,6605-49-8,6614-80-8,16908-86-4,19694-63-4,23567-09-1,34279-92-0,52340-87-1,54422-83-2,62138-03-8,62138-07-2,79391-04-1,89194-80-9,90080-19-6,92418-92-3,136457-84-6,136598-73-7)

Guidance literature:

With sodium hydroxide; In methanol; for 5h;

Reference yield:

3,4,6-tri-O-acetyl-1,2-O-(1-ethoxyethylidene)-β-D-mannopyranoside (28140-37-6) → 1-O-α-D-mannopyranosyl-sn-myo-inositol (2347-99-1,3687-64-7,4539-73-5,4572-85-4,4623-85-2,6605-49-8,6614-80-8,16908-86-4,19694-63-4,23567-09-1,34279-92-0,52340-87-1,54422-83-2,62138-03-8,62138-07-2,79391-04-1,89194-80-9,90080-19-6,92418-92-3,136457-84-6,136598-73-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 69.9 percent / 2,6-lutidinium perchlorate / 1,2-dichloro-ethane / 6 h / Heating; 4 Angstroem molecular sieves

2: 71.4 percent / 1percent aq.NaOH / methanol / 5 h

With sodium hydroxide; 2,6-lutidinium perchlorate; In methanol; 1,2-dichloro-ethane;

upstream raw materials:

1-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-3,4,5,6-tetra-O-acetyl-sn-myo-inositol

1-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-2,3,4,5,6-penta-O-acetyl-sn-myo-inositol

3,4,6-tri-O-acetyl-1,2-O-(1-ethoxyethylidene)-β-D-mannopyranoside

2,3,4,6-tetra-O-acetyl-β-D-mannopyranosyl fluoride

Downstream raw materials:

1-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-2,3,4,5,6-penta-O-acetyl-sn-myo-inositol

Refernces

• 1、 Sibrikov, Yu. I.,Stepanov, A. E.,Shvets, V. I.. "DERIVATIVES OF ASYMMETRICALLY SUBSTITUTED MYO-INOSITOL. XXXIII. SYNTHESIS OF DIASTEROMERIC MANNOSIDES OF MYO-INOSITOL". . p. 470 - 476. Retrieved 2007/10/02.